H1N1 influenza vaccination in HIV-infected women on effective antiretroviral treatment did not induce measurable antigen-driven proliferation of the HIV-1 proviral reservoir

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• 作者：Thor A. Wagner ; Hannah C. Huang ; Christen E. Salyer…
• 关键词：HIV ; HIV DNA ; Influenza ; Vaccination ; H1N1 ; Pregnancy ; Antiretroviral therapy ; Latency ; Antiretroviral treatment
• 刊名：AIDS Research and Therapy
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：14
• 期：1
• 全文大小：804KB
• 刊物主题：Infectious Diseases; Virology;
• 出版者：BioMed Central
• ISSN：1742-6405
• 卷排序：14

文摘

ObjectivesAntigen-induced activation and proliferation of HIV-1-infected cells is hypothesized to be a mechanism of HIV persistence during antiretroviral therapy. The objective of this study was to determine if proliferation of H1N1-specific HIV-infected cells could be detected following H1N1 vaccination.