H5-based DNA constructs derived from selected highly pathogenic H5N1 avian influenza virus induce high levels of humoral antibodies in Muscovy ducks against low pathogenic viruses
详细信息 查看全文
- 作者：Olivier Guionie ; éric Niqueux ; Michel Amelot ; Stéphanie Bougeard…
- 关键词：Avian influenzavirus ; H5 ; DNA immunization ; Duck ; Hemagglutination inhibition ; Virus neutralization ; Cross ; reactions
- 刊名：Virology Journal
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：11
- 期：1
- 全文大小：249 KB
- 参考文献：1. Swayne, DE, Halvorson, DA Influenza. In: Saif, YM eds. (2008) Diseases of Poultry. Blackwell Publishing, Ames, Iowa, pp. 153-184
Annual report on surveillance for avian influenza in poultry in member states of the European Union in 2011. European Commission, DG for Health and Consumers; AHVLA, Weybridge
2. To, KKW, Ng, KHL, Que, TL, Chan, JMC, Tsang, KY, Tsang, AKL, Chen, H, Yuen, KY (2012) Avian influenza A H5N1 virus: A continuous threat to humans. Emerging Microbes Infect 1: pp. e25 CrossRef
3. Chen, Y, Liang, W, Yang, S, Wu, N, Gao, H, Sheng, J, Yao, H, Wo, J, Fang, Q, Cui, D, Li, Y, Yao, X, Zhang, Y, Wu, H, Zheng, SJ, Diao, H, Xia, S, Zhang, Y, Chan, KH, Tsoi, HW, Teng, J, Song, W, Wang, P, Lau, SY, Zheng, M, Chan, J, To, KK, Chen, H, Li, L, Yuen, KY (2013) Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome. Lancet 381: pp. 1916-1925 CrossRef
4. Swayne, DE (2012) Impact of vaccines and vaccination on global control of avian influenza. Avian Dis 56: pp. 818-828 CrossRef
5. Marangon, S, Busani, L (2007) The use of vaccination in poultry production. Rev Sci Tech 26: pp. 265-274
6. Suarez, DL (2012) DIVA vaccination strategies for avian influenza virus. Avian Dis 56: pp. 836-844 CrossRef
7. Li, C, Bu, Z, Chen, H (2014) Avian influenza vaccines against H5N1 'bird flu'. Trends Biotechnol 32: pp. 147-156 CrossRef
8. Chen, H (2009) Avian influenza vaccination: The experience in China. Rev Sci Tech 28: pp. 267-274
9. Rauw, F, Palya, V, Van Borm, S, Welby, S, Tatar-Kis, T, Gardin, Y, Dorsey, KM, Aly, MM, Hassan, MK, Soliman, MA, Lambrecht, B, van den Berg, T (2011) Further evidence of antigenic drift and protective efficacy afforded by a recombinant HVT-H5 vaccine against challenge with two antigenically divergent Egyptian clade 2.2.1 HPAI H5N1 strains. Vaccine 29: pp. 2590-2600 vaccine.2011.01.048" target="_blank" title="It opens in new window">CrossRef
10. Bublot, M, Pritchard, N, Swayne, DE, Selleck, P, Karaca, K, Suarez, DL, Audonnet, JC, Mickle, TR (2006) Development and use of fowlpox vectored vaccines for avian influenza. Ann N Y Acad Sci 1081: pp. 193-201 CrossRef
11. Sarfati-Mizrahi, D, Lozano-Dubernard, B, Soto-Priante, E, Castro-Peralta, F, Flores-Castro, R, Loza-Rubio, E, Gay-Gutierrez, M (2010) Protective dose of a recombinant Newcastle disease LaSota-avian influenza virus H5 vaccine against H5N2 highly pathogenic avian influenza virus and velogenic viscerotropic Newcastle disease virus in broilers with high maternal antibody levels. Avian Dis 54: pp. 239-241 CrossRef
12. van den Berg, T, Lambrecht, B, Marche, S, Steensels, M, Van Borm, S, Bublot, M (2008) Influenza vaccines and vaccination strategies in birds. Comp Immunol Microbiol Infect Dis 31: pp. 121-165 CrossRef
13. Peyre, M, Fusheng, G, Desvaux, S, Roger, F (2009) Avian influenza vaccines: A practical review in relation to their application in the field with a focus on the Asian experience. Epidemiol Infect 137: pp. 1-21 CrossRef
14. Spackman, E, Swayne, DE (2013) Vaccination of gallinaceous poultry for H5N1 highly pathogenic avian influenza: Current questions and new technology. Virus Res 178: pp. 121-132 CrossRef
15. Bonfante, F, Gardin, Y, Terregino, C, Berton, V, Giasuddin, M, Das, BC, Yamage, M, Palya, V, Capua, I (2013) Efficacy of a single dose of rHVT-H5 avian influenza vector vaccine against a clade 2.3.2.1 of H5N1 highly pathogenic virus [abstract]. Proceedings of the 18th WVPAC2013: 29-3 August 2013; Nantes, France. pp. 451
16. Jiang, Y, Yu, K, Zhang, H, Zhang, P, Li, - 刊物主题：Virology;
- 出版者：BioMed Central
- ISSN：1743-422X
文摘
Background H5 low pathogenic avian influenza virus (LPAIV) infection in domestic ducks is a major problem in duck producing countries. Their silent circulation is an ongoing source of potential highly pathogenic or zoonotic emerging strains. To prevent such events, vaccination of domestic ducks might be attempted but remains challenging. Currently licensed vector vaccines derived from H5N1 HPAIV possess clade 0, clade 2.2 or clade 2.3.4 HA sequences: selection of the best HA candidate inducing the largest cross protection is a key issue. For this purpose, DNA immunization of specific pathogen free Muscovy ducks was performed using different synthetic codon optimized (opt) or native HA genes from H5N2 LPAIV and several H5N1 HPAIV clade 2.1, 2.2.1 and 2.3.4. Humoral cross-immunity was assessed 3?weeks after boost by hemagglutination inhibition (HI) and virus neutralization (VN) against three French H5 LPAIV antigens. Findings Vaccination with LP H5N2 HA induced the highest VN antibody titre against the homologous antigen; however, the corresponding HI titre was lower and comparable to HI titres obtained after immunization with opt HA derived from clades 2.3.4 or 2.1. Compared to the other HPAIV-derived constructs, vaccination with clade 2.3.4 opt HA consistently induced the highest antibody titres in HI and VN, when tested against all three H5 LPAIV antigens and H5N2 LPAIV, respectively: differences in titres against this last strain were statistically significant. Conclusion The present study provides a standardized method to assess cross-immunity based on HA immunogenicity alone, and suggests that clade 2.3.4-derived recombinant vaccines might be the optimal candidates for further challenge testing to vaccinate domestic Muscovy ducks against H5 LPAIV.