Construction of a recombinant Lactococcus lactis strain expressing a fusion protein of Omp22 and HpaA from Helicobacter pylori for oral vaccine development

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• 作者：Rongguang Zhang ; Guangcai Duan ; Qingfeng Shi ; Shuaiyin Chen…
• 关键词：Fusion protein ; Helicobactor pylori ; hpaA ; Lactococcus lactis ; omp22 ; Oral vaccine
• 刊名：Biotechnology Letters
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：38
• 期：11
• 页码：1911-1916
• 全文大小：557 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Microbiology
  Biotechnology
  Applied Microbiology
  Biochemistry
  
• 出版者：Springer Netherlands
• ISSN：1573-6776
• 卷排序：38

文摘

ObjectivesTo develop orally administrated anti-Helicobacter pylori vaccination, a Lactococcus lactis strain was genetically constructed for fusion expression of H. pylori protective antigens HpaA and Omp22.