Synthesis and biological activity of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine

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• 作者：N. V. Shtyrlin ; R. M. Vafina ; M. V. Pugachev ; R. M. Khaziev…
• 关键词：Key words3 ; hydroxypyridine ; 4 ; deoxypyridoxine ; phosphonium salts ; antibacterial activity ; antitumor activity
• 刊名：Russian Chemical Bulletin
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：65
• 期：2
• 页码：537-545
• 全文大小：329 KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistryr>Chemistryr>Organic Chemistryr>Inorganic Chemistryr>Russian Library of Sciencer>
• 出版者：Springer New York
• ISSN：1573-9171
• 卷排序：65

文摘

Methods for the synthesis of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine were developed. Some of obtained compounds possess high antibacterial and antitumor activity in vitro.