Helicobacter pylori au Burundi : première évaluation de la prévalence en endoscopie et de l’éradication
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- 作者：R. Ntagirabiri (1) (2)
S. Harerimana (1)
F. Makuraza (1)
E. Ndirahisha (1)
H. Kaze (1) (2)
A. Moibeni (1) - 关键词：Prévalence ; Helicobacter pylori ; éradication ; Résistance antibiotique ; Prevalence ; Helicobacter pylori ; Eradication ; Antibiotic resistance
- 刊名：Journal Africain d'H篓娄pato-Gastroent篓娄rologie
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：8
- 期：4
- 页码：217-222
- 全文大小：140 KB
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文摘
Aim The Helicobacter pylori (H. pylori) eradication induces the healing of gastroduodenal lesions and avoids the evolution into a gastric adenocarcinoma or into a mucosa-associated lymphoid tissue (MALT) lymphoma. The aim of the study was to determine the prevalence of H. pylori among patients attending medical cares and the efficiency of antibiotics accessible in our country for its eradication. Methods This is a randomized prospective study which included patients who underwent upper endoscopy with a research of H. pylori. The diagnosis and the assessment of H. pylori eradication have been made on gastric biopsies by a rapid urease test, the He-Py Test Gold?. Results A total of 257 patients have been included. The prevalence of H. pylori was estimated to 70,8%. The rate of H. pylori eradication was 18,7% by the regimen of Omeprazole 20 mg + Metronidazole 500 mg + Amoxicilline 1000 mg (OMA) twice a day during 7 days. It was 59,3% by the OMA 10 days and 84,6% by the regimen of Omeprazole 20 mg + Clarithromycine 500 mg + Amoxicillin 1000 mg (OCA) twice a day during 10 days. Conclusion The prevalence of H. pylori is high in our country. The rate of its eradication with the metronidazole is very low. A coordinated use of clarithromycine should be initiated in our country to protect its efficiency, which seems to be high.