Plant viruses as scaffolds for the presentation of vaccine epitopes

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• 作者：H. Plchova ; N. Cerovska ; P. Vaculik ; T. Moravec
• 关键词：Additional key wordstransient expression ; plant viral expression vectors
• 刊名：Biologia Plantarum
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：61
• 期：1
• 页码：1-12
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Plant Sciences;
• 出版者：Springer Netherlands
• ISSN：1573-8264
• 卷排序：61

文摘

Within the last two decades, plant viral vectors have emerged as an excellent tool for the expression of foreign peptides and proteins. Virus particles carrying foreign antigenic epitopes present some interesting advantages for vaccine design and other applications. This review covers recent advances in the use of some typical plant viruses with helical particles that present heterologous peptides with particular emphasis on particles derived from the Potato virus X (PVX) and its uses.