Confocal scanning laser ophthalmoscope in the retromode imaging modality in exudative age-related macular degeneration

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• 作者：Elisabetta Pilotto (1)
  Patrik Sportiello (1)
  Ernesto Alemany-Rubio (1) (2)
  Stela Vujosevic (3)
  Sara Segalina (1)
  Iva Fregona (1)
  Edoardo Midena (1) (3)
  
• 关键词：Retromode retinal imaging ; Confocal scanning laser ophthalmoscope ; Optical coherence tomography ; Fundus autofluorescence ; Exudative age ; related macular degeneration
• 刊名：Graefe's Archive for Clinical and Experimental Ophthalmology
• 出版年：2013
• 出版时间：January 2013
• 年：2013
• 卷：251
• 期：1
• 页码：27-34
• 全文大小：501KB
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• 作者单位：Elisabetta Pilotto (1)
  Patrik Sportiello (1)
  Ernesto Alemany-Rubio (1) (2)
  Stela Vujosevic (3)
  Sara Segalina (1)
  Iva Fregona (1)
  Edoardo Midena (1) (3)
  
  1. Department of Ophthalmology, University of Padova, via Giustiniani 2, 35128, Padova, Italy
  2. The Cuban Eye Institute “Ramon Pando Ferrer- The Havana, Cuba
  3. Fondazione G.B. Bietti per l’Oftalmologia, IRCCS, Rome, Italy
  
• ISSN：1435-702X

文摘

Purpose To evaluate the ability of confocal scanning laser ophthalmoscope (cSLO) in the retromode imaging modality in detecting retinal changes secondary to exudative age-related macular degeneration (AMD). Methods Seventeen eyes of 13 consecutive patients affected by CNV secondary to AMD were evaluated with optical coherence tomography (OCT) to detect neuroretinal detachment (NRD), pigment epithelial detachment (PED), cystoid macular edema (CME), and epiretinal membranes (ERM). All eyes were examined with a cSLO equipped with infrared retromode (RM) imaging modality. Infrared and fundus autofluorescence images were also obtained (IR and FAF). The intermethod agreement between OCT and cSLO was evaluated considering single cSLO imaging modality separately (IR, FAF, and RM), and all imaging modalities together. Results Eight eyes (47?%) had NRD at OCT; intermethod agreement was poor for any single cSLO imaging modality considered separately (k: 0.14, 0.01, and 0.29 for cSLO IR, FAF, and RM, respectively). Four eyes had PED at OCT (24?%); intermethod agreement was mild for cSLO RM, poor for IR and FAF (k: 0.51, 0.16, and 0.00, respectively). CME was present in eight eyes (47?%); intermethod agreement was excellent for cSLO RM, poor for IR and FAF (k: 0.88, 0.38, and 0.26, respectively). ERM was present in three eyes (18?%); intermethod agreement was mild for cSLO IR, poor for FAF, and excellent for RM (k: 0.59, 0.00, and 0.76, respectively). Conclusions cSLO RM imaging is a useful and reproducible technique in detecting retinal features associated with CNV, particularly CME.