Dimensionless study on dynamics of pressure controlled mechanical ventilation system

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• 作者：Yan Shi (1) (2)
  Jinglong Niu (1)
  Maolin Cai (1)
  Weiqing Xu (1)
  
• 关键词：Mechanical ventilation ; Pneumatic system ; Dimensionless dynamics ; Modeling simulation ; Experimental study
• 刊名：Journal of Mechanical Science and Technology
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：29
• 期：2
• 页码：431-439
• 全文大小：641 KB
• 参考文献：1. F. T. Tehrani, A control system for mechanical ventilation of passive and active subjects, / Journal of Computer Methods and Programs in Biomedicine, 110 (2013) 511鈥?18. CrossRef
  2. S. P. Pilbeam and J. M. Cairo, / Mechanical ventilation, physiological and clinical application, fourth ed., Mosby Elsevier, St. Louis (2006).
  3. R. L. Chatburn, Classification of ventilator modes, Update and proposal for implementation, / Respiratory Care, 52 (2007) 301鈥?23.
  4. A. Rajagiri, B. Diong, M. Goldman and H. Nazeran, Can asthma in children be detected by the estimated parameter values of the augmented RIC model?, / Proceedings of Conference of IEEE Eng. Med. Biol. Soc., 1 (2006) 5595鈥?598. CrossRef
  5. C. Ionescu, E. Derom and R. De Keyser, Assessment of respiratory mechanical properties with constant-phase models in healthy and COPD lungs, / Computers in Methods Programs Biomed., 97 (1) (2010) 78鈥?5. CrossRef
  6. J. Chmielecki et al., Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling, / Sci. Transl. Med., 3 (90) (2011) 90ra59. CrossRef
  7. H. Koc et al., The role of mathematical modeling in VOC analysis using isoprene as a prototypic example, / J. Breath Res. report and papers, 5 (2011) http://dx.doi.org/10.1088/1752-7155/5/3/037102.
  8. J. Szaleniec, J. Skladzien, R. Tadeusiewicz, K. Oles, M. Konior and R. Przeklasa, How can an otolaryngologist benet from arti cial neural networks?, / Otolaryngol. Pol., 66 (2012) 241鈥?48. CrossRef
  9. R. Sturm, A computer model for the simulation of ber-cell interaction in the alveolar region of the respiratory tract, / Computers in Biology and Medicine, 41 (2011) 565鈥?73. CrossRef
  10. G. Avanzolini et al., A new approach for tracking respiratory mechanical parameters in real-time, / Annals of Biomedical Engineering, 25 (1997) 154鈥?63. CrossRef
  11. A. G. Polak and J. Mroczka, Nonlinear model for mechanical ventilation of human lungs, / Computers in Biology and Medicine, 36 (2006) 41鈥?8. CrossRef
  12. R. Grzegorz and J. Jacek, A new approach to modeling of selected human respiratory system diseases, directed to computer simulations, / Computers in Biology and Medicine, 43 (2013) 1606鈥?613. CrossRef
  13. W. Tomalak, Wybrane aspekty badania mechaniki oddychania i modelowania systemu oddechowego przy uzyciu techniki oscylacji wymuszonych, / Sc.D. Dissertation (1998) IGiCP.ZP; Rabka.
  14. J. Eyles and R. Pimmel, Estimating respiratory mechanical parameters in parallel compartment models, / IEEE Transations on Biomed. Engineering, 4 (1981) 313鈥?17. CrossRef
  15. B. Diong, M. Goldman and H. Nazeran, Respiratory impedance values in adults are relatively insensitive to mead model lung compliance and chest wall compliance parameters, / Proceedings of IFMBE, 32 (2010) 201鈥?03. CrossRef
  16. M. P. Vassiliou et al., Volume and flow dependence of respiratory mechanics in mechanically ventilated COPD patients, / Journal of Respiratory Physiology & Neurobiology, 135 (2003) 87鈥?6. CrossRef
  17. L. Robert, Computer control of mechanical ventilation, / Respiratory Care, 49 (5) (2004) 507鈥?15.
  18. J. X. Brunner, / History and Principles of Closed-Loop Control Applied to Mechanical Ventilation, Hamilton Medical AG, Rhazuns (2002).
  19. M. Borrello, Modeling and control of systems for critical care ventilation, / Proceeding of the 2005 American control conference, Portland, OR, USA (2005) 2166鈥?180.
  20. Y. Shi and M. Cai, Working characteristics of two kinds of air-driven boosters, / Journal of Energy Conversion and Management, 52 (2011) 3399鈥?407. CrossRef
  21. M. Cai, K. Kawashima and T. Kagawa, Power assessment of flowing compressed sir, / Journal of Fluids Engineering, Transactions of the ASME, 128 (2) (2006) 402鈥?05. CrossRef
  22. Y. Shi et al., Pressure dynamic characteristics of pressure controlled ventilation system of a lung simulator[J], / Computational and mathematical methods in medicine (2014).
  23. Y. Shi et al., Modelling and simulation of volume controlled mechanical ventilation system[J], / Mathematical Problems in Engineering (2014).
  
• 作者单位：Yan Shi (1) (2)
  Jinglong Niu (1)
  Maolin Cai (1)
  Weiqing Xu (1)
  
  1. School of Automation Science and Electrical Engineering, Beihang University, Beijing, 100191, China
  2. Department of Mechanical Engineering, University of Bath, Bath, BA2 7AY, UK
  
• 刊物类别：Engineering
• 刊物主题：Mechanical Engineering
  Structural Mechanics
  Control Engineering
  Industrial and Production Engineering
  
• 出版者：The Korean Society of Mechanical Engineers
• ISSN：1976-3824

文摘

Dynamics of mechanical ventilation system can be referred in pulmonary diagnostics and treatments. In this paper, to conveniently grasp the essential characteristics of mechanical ventilation system, a dimensionless model of mechanical ventilation system is presented. For the validation of the mathematical model, a prototype mechanical ventilation system of a lung simulator is proposed. Through the simulation and experimental studies on the dimensionless dynamics of the mechanical ventilation system, firstly, the mathematical model is proved to be authentic and reliable. Secondly, the dimensionless dynamics of the mechanical ventilation system are obtained. Last, the influences of key parameters on the dimensionless dynamics of the mechanical ventilation system are illustrated. The study provides a novel method to study the dynamic of mechanical ventilation system, which can be referred in the respiratory diagnostics and treatment.