Evaluation of six novel antigens as potential biomarkers for the early immunodiagnosis of schistosomiasis
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- 作者：Yuanbin Zhang ; Jing Zhao ; Xinye Wang ; Xindong Xu ; Weiqing Pan
- 关键词：Schistosoma japonicum ; Schistosomiasis ; Biomarker ; Early diagnosis ; Animal model
- 刊名：Parasites & Vectors
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：8
- 期：1
- 全文大小：1,028 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine; Entomology;
- 出版者：BioMed Central
- ISSN：1756-3305
文摘
Background Early diagnosis of schistosomiasis, prior to egg laying, would enable earlier treatment and help interrupt the transmission cycle of the parasite and the progress of the disease. Previously we identified six novel antigens with potential as diagnostic markers for human Schistosoma japonicum infections. In this study, we evaluated these antigens as candidate biomarkers for the early diagnosis of schistosomiasis in mice and rabbits.