The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information

详细信息    查看全文

• 作者：G Thomas Hayman (1)
  Pushkala Jayaraman (1)
  Victoria Petri (1)
  Marek Tutaj (1)
  Weisong Liu (1)
  Jeff De Pons (1)
  Melinda R Dwinell (1)
  Mary Shimoyama (1)
  
• 关键词：Curation ; Databases ; Ontologies ; Pathways ; Tools
• 刊名：Human Genomics
• 出版年：2013
• 出版时间：December 2013
• 年：2013
• 卷：7
• 期：1
• 全文大小：1355KB
• 参考文献：1. Jacob HJ: Functional genomics and rat models. / Genome Res 1999, 9:1013鈥?016. CrossRef
  2. Shimoyama M, Smith JR, Hayman T, Laulederkind S, Lowry T, Nigam R, Petri V, Wang SJ, Dwinell M, Jacob H, Team RGD: RGD: a comparative genomics platform. / Hum Genomics 2011, 5:124鈥?29. CrossRef
  3. Kemkemer C, Kohn M, Cooper DN, Froenicke L, H枚gel J, Hameister H, Kehrer-Sawatzki H: Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution. / BMC Evol Biol 2009, 9:84. CrossRef
  4. Shimoyama M, Hayman GT, Laulederkind SJ, Nigam R, Lowry TF, Petri V, Smith JR, Wang SJ, Munzenmaier DH, Dwinell MR, Twigger SN, Jacob HJ, Team RGD: The rat genome database curators: who, what, where, why. / PLoS Comput Biol 2009, 5:e1000582. CrossRef
  5. Laulederkind SJF, Shimoyama M, Hayman GT, Lowry TF, Nigam R, Petri V, Smith JR, Wang SJ, De Pons J, Kowalski G, Liu W, Rood W, Munzenmaier DH, Dwinell MR, Twigger SN, Jacob HJ, Team RGD: The Rat Genome Database curation tool suite: a set of optimized software tools enabling efficient acquisition, organization, and presentation of biological data. / Database 2011, 2011:bar002. CrossRef
  6. Petri V, Shimoyama M, Hayman GT, Smith JR, Tutaj M, De Pons J, Dwinell MR, Munzenmaier DH, Twigger SN, Jacob HJ, Team RGD: The Rat Genome Database pathway portal. / Database 2011, 2011:bar010. CrossRef
  7. Laulederkind SJ, Tutaj M, Shimoyama M, Hayman GT, Lowry TF, Nigam R, Petri V, Smith JR, Wang SJ, De Pons J, Dwinell MR, Jacob HJ: Ontology searching and browsing at the Rat Genome Database. / Database 2012, 2012:bas016. CrossRef
  8. Laulederkind SJF, Hayman GT, Wang SJ, Lowry TF, Nigam R, Petri V, Smith JR, Shimoyama M, Dwinell MR, Jacob HJ: Exploring genetic, genomic, and phenotypic data at the rat genome database. / Curr Protocols Bioinf in press
  9. Walls C, Breidenbach R: / Spring in Action. 2nd edition. Greenwich: Manning Publications; 2007.
  10. Crane D, Pascarello E, James D: / AJAX in Action. Greenwich: Manning Publications; 2005.
  
• 作者单位：G Thomas Hayman (1)
  Pushkala Jayaraman (1)
  Victoria Petri (1)
  Marek Tutaj (1)
  Weisong Liu (1)
  Jeff De Pons (1)
  Melinda R Dwinell (1)
  Mary Shimoyama (1)
  
  1. Rat Genome Database, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, 53226, USA
  
• ISSN：1479-7364

文摘

The RGD Pathway Portal provides pathway annotations for rat, human and mouse genes and pathway diagrams and suites, all interconnected via the pathway ontology. Diagram pages present the diagram and description, with diagram objects linked to additional resources. A newly-developed dual-functionality web application composes the diagram page. Curators input the description, diagram, references and additional pathway objects. The application combines these with tables of rat, human and mouse pathway genes, including genetic information, analysis tool and reference links, and disease, phenotype and other pathway annotations to pathway genes. The application increases the information content of diagram pages while expediting publication.