Rituximab-induced remission in a woman with coexisting rheumatoid arthritis and nephrotic syndrome

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• 作者：Mia Weiss ; Omer Gendelman ; Gilad Twig ; Ana Tobar&#8230
• 关键词：Rheumatoid arthritis ; Nephrotic syndrome ; Rituximab ; B cells ; Proteinuria
• 刊名：Rheumatology International
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：35
• 期：9
• 页码：1597-1600
• 全文大小：769 KB
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• 作者单位：Mia Weiss (1) (2) <br> Omer Gendelman (1) (2) <br> Gilad Twig (1) (2) (3) <br> Ana Tobar (4) <br> Howard Amital (1) (2) <br><br>1. Department of Medicine 鈥楤鈥? Sheba Medical Center, Tel-Hashomer, 52621, Israel <br> 2. Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel <br> 3. The Pinchas Borenstein Talpiot Medical leadership program, Sheba Medical Center, Tel-Hashomer, Israel <br> 4. Department of Pathology, Rabin Medical Center, Petach Tikva, Israel <br>
• 刊物主题：Rheumatology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1437-160X

文摘

We describe a patient with rheumatoid arthritis who presented with nephrotic syndrome which was not related neither to drug therapy nor to amyloidosis. Renal biopsy revealed membranous glomerulonephritis. The patient was treated with three cycles of rituximab with complete resolution of the clinical and laboratory evidence of nephrosis. The following report discusses this unusual presentation and clinical response.