Protocol for the ENCODE trial: evaluating a novel online depression intervention for persons with epilepsy
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- 作者：Björn Meyer ; Mario Weiss ; Martin Holtkamp ; Stephan Arnold ; Katja Brückner…
- 关键词：Epilepsy ; Depression ; Anxiety ; Internet interventions
- 刊名：BMC Psychiatry
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：787KB
- 刊物主题：Psychiatry; Psychotherapy;
- 出版者：BioMed Central
- ISSN：1471-244X
- 卷排序：17
文摘
BackgroundDepression is common among persons with epilepsy (PwE), affecting roughly one in three individuals, and its presence is associated with personal suffering, impaired quality of life, and worse prognosis. Despite the availability of effective treatments, depression is often overlooked and treated inadequately in PwE, in part because of assumed concerns over drug interactions or proconvulsant effects of antidepressants. Internet-administered psychological interventions might complement antidepressant medication or psychotherapy, and preliminary evidence suggests that they can be effective. However, no trial has yet examined whether an Internet intervention designed to meet the needs of PwE can achieve sustained reductions in depression and related symptoms, such as anxiety, when offered as adjunct to treatment as usual.