Measurement and Correlation Solubility of Sodium Succinate in Binary Mixed Solvents of Water + (Methanol or Ethanol) Mixtures

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• 作者：Zheng Cao (1)
  Yonghong Hu (1)
  Jiaojiao Li (1)
  Mengmeng Liang (1)
  Yan Liu (1)
  Wenge Yang (1)
  
• 关键词：Sodium succinate ; Solubility ; Modified Apelblat equation ; Solution thermodynamics
• 刊名：Journal of Solution Chemistry
• 出版年：2014
• 出版时间：May 2014
• 年：2014
• 卷：43
• 期：5
• 页码：821-835
• 全文大小：
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• 作者单位：Zheng Cao (1)
  Yonghong Hu (1)
  Jiaojiao Li (1)
  Mengmeng Liang (1)
  Yan Liu (1)
  Wenge Yang (1)
  
  1. College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, No. 200, North Zhongshan Road, Nanjing, 210009, China
  
• ISSN：1572-8927

文摘

The solubility of sodium succinate in binary solvent mixtures was measured by an analytical stirred-flask method in the temperature range 278.15-18.15?K at atmospheric pressure. It was found that the solubility of sodium succinate in the system increased with increasing temperature and decreased with the increasing mass fractions of methanol or ethanol. The modified Apelblat equation, the Buchwski–Ksiazaczak λh equation and the combined nearly ideal binary solvent/Redlich–Kister (CNIBS/R–K) equation were proposed for correlating the experimental data. The modified Apelblat equation was found to regress the solubility data much better than the Buchwski–Ksiazaczak equation and the CNIBS/R–K equation in a binary solvent system. The dissolution enthalpy and dissolution entropy of sodium succinate were calculated from the solubility data, using the Van’t Hoff equation. The experiment results and correlation models could be used as essential data in the purification of sodium succinate.