Increased prevalence of hepatitis C virus subtype 6a in China: a comparison between 2004-007 and 2008-011
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- 作者：Xia Rong (1)
Ru Xu (1)
Huaping Xiong (1)
Min Wang (1)
Ke Huang (1)
Qiuyu Chen (1)
Chengyao Li (2)
Qiao Liao (1)
Jieting Huang (1)
Wenjie Xia (1)
Guangping Luo (1)
Xin Ye (1)
Ming Zhang (3)
Yongshui Fu (1) - 刊名：Archives of Virology
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：159
- 期：12
- 页码：3231-3237
- 全文大小：569 KB
- 参考文献：1. Global Burden of Hepatitis C Working Group (2004) Global burden of disease (GBD) for hepatitis C. J Clin Pharmacol 44(1):20-9
2. Smith DB, Bukh J, Kuiken C, Muerhoff AS, Rice CM, Stapleton JT, Simmonds P (2014) Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment Web resource. Hepatology 59:318-27 CrossRef
3. Simmonds P, Bukh J, Combet C, Deleage G, Enomoto N, Feinstone S, Halfon P, Inchauspe G, Kuiken C, Maertens G, Mizokami M, Murphy DG, Okamoto H, Pawlotsky JM, Penin F, Sablon E, Shin IT, Stuyver LJ, Thiel HJ, Viazov S, Weiner AJ, Widell A (2005) Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 42:962-73 CrossRef
4. Mahaney K, Tedeschi V, Maertens G, Di Bisceglie AM, Vergalla J, Hoofnagle JH, Sallie R (1994) Genotypic analysis of hepatitis C virus in American patients. Hepatology 20:1405-411 CrossRef
5. Grassi E, Aghemo A (2013) How to optimize HCV therapy in genotype 2 patients. Liver Int 33(Suppl 1):35-0 CrossRef
6. Lagging M, Rembeck K, Rauning Buhl M, Christensen P, Dalgard O, Farkkila M, Hellstrand K, Langeland N, Lindh M, Westin J, Norkrans G (2013) Retreatment with peg-interferon and ribavirin in patients with chronic hepatitis C virus genotype 2 or 3 infection with prior relapse. Scand J Gastroenterol 48:839-47 CrossRef
7. Abe H, Aida Y, Ishiguro H, Yoshizawa K, Seki N, Miyazaki T, Itagaki M, Sutoh S, Ika M, Kato K, Shimada N, Tsubota A, Aizawa Y (2013) New proposal for response-guided peg-interferon-plus-ribavirin combination therapy for chronic hepatitis C virus genotype 2 infection. J Med Virol 85:1523-533 CrossRef
8. Inamullah IM, Ahmed H, Sajidulg AM, Ali L, Ahmed A (2011) Hepatitis C virus genotypes circulating in district Swat of Khyber Pakhtoonkhaw, Pakistan. Virol J 8:16 CrossRef
9. Chakravarti A, Ashraf A, Malik S (2013) A study of changing trends of prevalence and genotypic distribution of hepatitis C virus among high risk groups in North India. Indian J Med Microbiol 31:354-59 CrossRef
10. Verbeeck J, Maes P, Lemey P, Pybus OG, Wollants E, Song E, Nevens F, Fevery J, Delport W, Van der Merwe S, Van Ranst M (2006) Investigating the origin and spread of hepatitis C virus genotype 5a. J Virol 80:4220-226 CrossRef
11. Akkarathamrongsin S, Praianantathavorn K, Hacharoen N, Theamboonlers A, Tangkijvanich P, Tanaka Y, Mizokami M, Poovorawan Y (2010) Geographic distribution of hepatitis C virus genotype 6 subtypes in Thailand. J Med Virol 82:257-62 CrossRef
12. Nguyen NH, Vutien P, Trinh HN, Garcia RT, Nguyen LH, Nguyen HA, Nguyen KK, Nguyen MH (2010) Risk factors, genotype 6 prevalence, and clinical characteristics of chronic hepatitis C in Southeast Asian Americans. Hepatol Int 4:523-29 CrossRef
13. Lu L, Nakano T, He Y, Fu Y, Hagedorn CH, Robertson BH (2005) Hepatitis C virus genotype distribution in China: predominance of closely related subtype 1b isolates and existence of new genotype 6 variants. J Med Virol 75:538-49 CrossRef
14. Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, Goodman ZD, Koury K, Ling M, Albrecht JK (2001) Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358:958-65 CrossRef
15. Fried MW, Shiffman ML, Reddy KR, Smith C, Ma - 作者单位：Xia Rong (1)
Ru Xu (1)
Huaping Xiong (1)
Min Wang (1)
Ke Huang (1)
Qiuyu Chen (1)
Chengyao Li (2)
Qiao Liao (1)
Jieting Huang (1)
Wenjie Xia (1)
Guangping Luo (1)
Xin Ye (1)
Ming Zhang (3)
Yongshui Fu (1)
1. Guangzhou Blood Center, 31 Lu Yuan Road, Guangzhou, 510095, Guangdong, China
2. Department of Transfusion Medicine, School of Biotechnology, Southern Medical University, Guangzhou, Guangdong, China
3. Department of Epidemiology and Biostatistics, Faculty of Infectious Diseases, University of Georgia, Rm226 Miller Hall Building, Health Sciences Campus, Athens, GA, 30622, USA - ISSN：1432-8798
文摘
Different hepatitis C virus (HCV) genotypes exhibit differences in disease pathogenesis and progression, as well as disease outcomes and response to therapy. Tracking the change of HCV genotypes in various epidemiological settings is critical for both disease surveillance and the development of improved antiviral treatment. Here, we tracked the changes in the prevalence of the HCV genotypes in China between 2004-2007 and 2008-2011. HCV-RNA-positive sera were collected from volunteer blood donors during the period 2008-2011. The genotypes were determined by phylogenic analysis using the NS5B and E1 sequences. Geographical and demographic distribution patterns related to the HCV genotypes obtained in 2008-2011 were compared with our previous study, which recorded data in the period 2004-2007. Pearson chi-square test and t-test were used to statistically analyze the results. In 2008-2011, HCV subtypes 1b and 6a were detected in 43.8?% (184/420) and 34.3?% (144/420), respectively. The male/female ratio was found to be higher for HCV genotype 6 than for genotypes 1 and 2. When compared with the period of 2004-2007, although no significant difference was found in gender or age for genotypes 1, 2, 3 and 6, the subtype 6a frequency was significantly increased from 11?% to 26.5?% in the blood donors from outside of Guangdong Province in 2008-2011. A pattern of increase in HCV subtype 6a was found in blood donors outside of Guangdong Province, indicating that HCV subtype 6a has rapidly spread from Guangdong to other regions of China over the past 10 years.