Dysregulated microRNAs involved in the progression of cervical neoplasm

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• 作者：Kangkang Zeng ; Wenjing Zheng ; Xianglan Mo ; Fei Liu…
• 关键词：Cervical cancer ; Cervical intraepithelial neoplasia ; MicroRNA
• 刊名：Archives of Gynecology and Obstetrics
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：292
• 期：4
• 页码：905-913
• 全文大小：830 KB
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• 作者单位：Kangkang Zeng (1)
  Wenjing Zheng (2)
  Xianglan Mo (3)
  Fei Liu (4)
  Meiyi Li (1)
  Zhen Liu (2)
  Wei Zhang (2)
  Xiaoxia Hu (1)
  
  1. Department of Gynecology, The People鈥檚 Hospital of Guangxi Zhuang Autonomous Region, 6 Taoyuan Road, Nanning, 530021, Guanxi, People鈥檚 Republic of China
  2. Department of Gynecology, Renmin Hospital of Wuhan University, 99 Ziyang Road, Wuchang District, Wuhan, 430060, Hubei, People鈥檚 Republic of China
  3. Department of Pathology, The People鈥檚 Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guanxi, People鈥檚 Republic of China
  4. Research Center of Medical Science, The People鈥檚 Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guanxi, People鈥檚 Republic of China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Gynecology
  Obstetrics and Perinatology
  Endocrinology
  Human Genetics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0711

文摘

Purpose MicroRNAs (miRNAs) exhibit dysregulated expression in human cancer and play an important role in carcinogenesis. The aim of this study was to identify a distinct miRNA expression signature for cervical cancer and cervical intraepithelial neoplasia (CIN) and to investigate the function of deregulated miRNAs in cervical carcinoma.