Amplitude-based optimal respiratory gating in positron emission tomography in patients with primary lung cancer
详细信息 查看全文
- 作者：Willem Grootjans (1)
Lioe-Fee de Geus-Oei (1) (2)
Antoi P. W. Meeuwis (1)
Charlotte S. van der Vos (1)
Martin Gotthardt (1)
Wim J. G. Oyen (1)
Eric P. Visser (1) - 关键词：Respiratory gating ; Standardized uptake value ; 18?F ; FDG ; PET/CT ; Lung cancer
- 刊名：European Radiology
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：24
- 期：12
- 页码：3242-3250
- 全文大小：4,038 KB
- 参考文献：1. Bentzen SM, Gregoire V (2011) Molecular Imaging–Based Dose Painting: A Novel Paradigm for Radiation Therapy Prescription. Semin Radiat Oncol 2:101-10 CrossRef
2. Berghmans T, Dusart M, Paesmans M et al (2008) Primary Tumor Standardized Uptake Value (SUVmax) Measured on Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) is of Prognostic Value for Survival in Non-small Cell Lung Cancer (NSCLC): A Systematic Review and Meta-Analysis (MA) by the European Lung Cancer Working Party for the IASLC Lung Cancer Staging Project. J Thorac Oncol 1:6-2 CrossRef
3. Bettinardi V, Picchio M, Di Muzio N, Gilardi MC (2012) Motion Management in Positron Emission Tomography/Computed Tomography for Radiation Treatment Planning. Semin Nucl Med 5:289-07 CrossRef
4. Bomanji JB, Costa DC, Ell PJ (2001) Clinical role of positron emission tomography in oncology. Lancet Oncol 3:157-64 CrossRef
5. Callahan J, Binns D, Dunn L, Kron T (2011) Motion effects on SUV and lesion volume in 3D and 4D PET scanning. Australas Phys Eng Sci Med 4:489-95 CrossRef
6. Carney JPJ, Townsend DW, Rappoport V, Bendriem B (2006) Method for transforming CT images for attenuation correction in PET/CT imaging. Med Phys 4:976-83 CrossRef
7. Chang G, Chang T, Pan T, Clark JW, Mawlawi OR (2010) Implementation of an Automated Respiratory Amplitude Gating Technique for PET/CT: Clinical Evaluation. J Nucl Med 1:16-4 CrossRef
8. Chen HHW, Chiu N-T, Su W-C, Guo H-R, Lee B-F (2012) Prognostic Value of Whole-Body Total Lesion Glycolysis at Pretreatment FDG PET/CT in Non–Small Cell Lung Cancer. Radiology 2:559-66 CrossRef
9. Dawood M, Buther F, Lang N, Schober O, Schafers KP (2007) Respiratory gating in positron emission tomography: A quantitative comparison of different gating schemes. Med Phys 7:3067-076 CrossRef
10. de Geus-Oei L-F, van der Heijden HFM, Visser EP et al (2007) Chemotherapy Response Evaluation with 18?F-FDG PET in Patients with Non-Small Cell Lung Cancer. J Nucl Med 10:1592-598
11. de Geus-Oei LF, van Laarhoven HWM, Visser EP et al (2008) Chemotherapy response evaluation with FDG–PET in patients with colorectal cancer. Ann Oncol 2:348-52 CrossRef
12. Dose Schwarz J, Bader M, Jenicke L, Hemminger G, J?nicke F, Avril N (2005) Early Prediction of Response to Chemotherapy in Metastatic Breast Cancer Using Sequential 18?F-FDG PET. J Nucl Med 7:1144-150
13. Elmpt W, Hamill J, Jones J, Ruysscher D, Lambin P, ?llers M (2011) Optimal gating compared to 3D and 4D PET reconstruction for characterization of lung tumours. Eur J Nucl Med Mol Imaging 5:843-55 CrossRef
14. Erdi YE, Malawi O, Larson SM et al (1997) Segmentation of Lung Lesion Volume by Adaptive Positron Emission Tomography Image Thresholding. Cancer 12:2505-509 CrossRef
15. Fletcher JW, Djulbegovic B, Soares HP et al (2008) Recommendations on the Use of 18?F-FDG PET in Oncology. J Nucl Med 3:480-08
16. Goerres G, Kamel E, Heidelberg T-N, Schwitter M, Burger C, von Schulthess G (2002) PET-CT image co-registration in the thorax: influence of respiration. Eur J Nucl Med Mol Imaging 3:351-60 CrossRef
17. Hoekstra CJ, Stroobants SG, Smit EF et al (2005) Prognostic Relevance of Response Evaluation Using [18?F]-2-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography in Patients With Locally Advanced Non–Sma - 作者单位：Willem Grootjans (1)
Lioe-Fee de Geus-Oei (1) (2)
Antoi P. W. Meeuwis (1)
Charlotte S. van der Vos (1)
Martin Gotthardt (1)
Wim J. G. Oyen (1)
Eric P. Visser (1)
1. Department of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands
2. MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands - ISSN：1432-1084
文摘
Objectives Respiratory motion during PET imaging introduces quantitative and diagnostic inaccuracies, which may result in non-optimal patient management. This study investigated the effects of respiratory gating on image quantification using an amplitude-based optimal respiratory gating (ORG) algorithm. Methods Whole body FDG-PET/CT was performed in 66 lung cancer patients. The respiratory signal was obtained using a pressure sensor integrated in an elastic belt placed around the patient’s thorax. ORG images were reconstructed with 50?%, 35?%, and 20?% of acquired PET data (duty cycle). Lesions were grouped into anatomical locations. Differences in lesion volume between ORG and non-gated images, and mean FDG-uptake (SUVmean) were calculated. Results Lesions in the middle and lower lobes demonstrated a significant SUVmean increase?for all duty cycles and volume decrease for duty cycles of 35 % and 20 %. Significant increase in SUVmean and decrease in volume for lesions in the upper lobes were observed for a 20?% duty cycle. The SUVmean increase for central lesions was significant for?all duty cycles, whereas a significant volume decrease was observed for a duty cycle of 20?%. Conclusions This study implies that ORG could influence clinical PET imaging with respect to response monitoring and radiotherapy planning. Key Points -Quantifying lesion volume and uptake in PET is important for patient management -Respiratory motion artefacts introduce inaccuracies in quantification of PET images -Amplitude-based optimal respiratory gating maintains image quality through selection of duty cycle -The effect of respiratory gating on lesion quantification depends on anatomical location