Improving Anesthesia Safety in Low-Income Regions of the World
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  • 作者:Isabeau A. Walker (1)
    Tom Bashford (2)
    J. E. Fitzgerald (3)
    Iain H. Wilson (4)
  • 关键词:Safety ; Low ; income countries ; Health infrastructure ; Resources ; Training ; Anesthesia equipment ; Quality improvement
  • 刊名:Current Anesthesiology Reports
  • 出版年:2014
  • 出版时间:June 2014
  • 年:2014
  • 卷:4
  • 期:2
  • 页码:90-99
  • 全文大小:230 KB
  • 参考文献:1. Trent JC, Gaster RN. Anesthetic deaths in 54,128 consecutive cases. Ann Surg. 1944;119:954鈥?. CrossRef
    2. Beecher HK, Todd DP. A study of the deaths associated with anesthesia and surgery, bases on a study of 599,548 anesthesias in ten institutions 1948鈥?952 inclusive. Ann Surg. 1954;140:2鈥?4. CrossRef
    3. Macintosh RR. Deaths under anaesthetics. Br J Anaesth. 1949;21:107鈥?6. CrossRef
    4. Committee on Quality of Health Care in America IoM. In: Kohn L, Corrigan J, Donaldson M, editors. To err is human: building a safer health system. Washington, DC: National Academy Press; 1999. p. 241.
    5. Buck N, Devlin HB, Lunn JN. The report of a confidential enquiry into perioperative deaths. London: Nuffield Provincial Hospitals Trust and the King鈥檚 Fund; 1987.
    6. Eichorn JH. Prevention of intraoperative anesthesia accidents and related severe injury through safety monitoring. Anesthesiology. 1989;70:572鈥?. CrossRef
    7. 鈥⑩€⒙燘ainbridge D, Martin J, Arango M, Cheng D, for the Evidence-based Peri-operative Clinical Outcomes Research (EPiCOR) Group. Perioperative and anaesthetic-related mortality in developed and developing countries: a systematic review and meta-analysis. Lancet. 2012;380:1075鈥?1. / Systematic review of anesthesia outcomes reported from the 1970s to 2011, showing how anesthesia mortality has improved in countries with a high development index, but not in those with a low development index.
    8. Heywood AJ, Wilson IH, Sinclair JR. Perioperative mortality in Zambia. Ann R Coll Surg Engl. 1989;71:354鈥?.
    9. Hansen D, Gausi SC, Merikebu M. Anaesthesia in Malawi: complications and deaths. Trop Doct. 2000;30:146鈥?.
    10. Glenshaw M, Madzimbamuto FD. Anaesthesia associated mortality in a district hospital in Zimbabwe: 1994 to 2001. Cent Afr J Med. 2005;51:39鈥?4.
    11. Ouro-Bang鈥檔a Maman AF, Tomta K, Ahouangbvi S, Chobli M. Deaths associated with anaesthesia in Togo, West Africa. Trop Doct. 2005;35:220鈥?. CrossRef
    12. Enohumah KO, Imarengiaye CO. Factors associated with anaesthesia-related maternal mortality in a tertiary hospital in Nigeria. Acta Anaesthesiol Scand. 2006;50:206鈥?0. CrossRef
    13. Walker IA, Wilson IH. Anaesthesia in developing countries鈥攁 risk for patients. Lancet. 2008;371:968鈥?. CrossRef
    14. Fenton P, Whitty CJM, Reynolds F. Caesarean section in Malawi: prospective study of early maternal and perinatal mortality. BMJ. 2003;327:587鈥?2. CrossRef
    15. 鈥⑩€⒙燚epartment of Health, Republic of South Africa. Saving mothers 2008-2010: Fifth report on the confidential enquiries into maternal deaths in South Africa. Anesthetic-related deaths. 2012 Ch 7 p. 124 http://www.doh.gov.za/docs/reports/2012/Report_on_Confidential_Enquiries_into_Maternal_Deaths_in_South_Africa.pdf. Accessed 15 Dec 2013. / Highlights preventable causes of anesthesia- / related maternal deaths in rural hospitals.
    16. 鈥⑩€⒙燱eiser TG, Regenbogen SE, Thompson KD et al. An estimation of the global volume of surgery: a modelling strategy based on available data. Lancet. 2008;372:139鈥?4 / Describes the deficit in surgical provision in low- / income countries.
    17. Galukande M, von Schreeb J, Wladis et al. Essential surgery at the district hospital: a retrospective descriptive analysis in three African countries. PLoS Med 2010;7:e1000243.
    18. Lavy C, Sauven K, Mkandawire N, et al. State of surgery in tropical Africa: a review. World J Surg. 2011;35:262鈥?1. CrossRef
    19. 鈥⒙燱alker IA, Obua AD, Mouton F, Ttendo S, Wilson IH. Paediatric surgery and anaesthesia in south-western Uganda: a cross-sectional survey. Bull World Health Organ. 2010;88:897鈥?06 / An account of the low volume of surgery performed in rural hospitals.
    20. Petroze RT, Groen RS, Niyonkuru F, et al. Estimating operative disease prevalence in a low-income country; results of a nationwide population survey in Rwanda. Surgery. 2013;153:457鈥?4. CrossRef
    21. 鈥⑩€⒙燝roen RS, Samai M, Stewart K-A et al. Untreated surgical conditions in Sierra Leone: a cluster randomised, cross-sectional, country-wide survey. Lancet 2012;380:1082鈥?7 / Describes a method of assessing the unmet surgical need in rural populations.
    22. Stewart K-A, Groen RS, Farahzad MM, et al. Traumatic injury in Sierra Leone: results from a nationwide survey. JAMA. 2013;148:463鈥?. CrossRef
    23. Zafar SN, Fatmi A, Iqbal, et al. Disparities in access to surgical care within a lower income country: an alarming inequity. World J Surg. 2013;37:1470鈥?. CrossRef
    24. Reshamwalla S, Gobeze AA, Ghosh S, et al. Snapshot of surgical activity in rural Ethiopia: is enough being done? World J Surg. 2012;36:1049鈥?5. CrossRef
    25. 鈥⑩€⒙燙avallaro FL, Cresswell JA, Franca GVA et al. Trends in caesarean delivery by country and wealth quintile: cross-sectional surveys in southern Asia and sub-Saharan Africa. Bull World Health Organ 2013; 91:914鈥?2. / Highlights the contribution of lack of access to surgery to poor maternal outcomes.
    26. 鈥⒙燜enton PM. The epidemiology of district surgery in Malawi: a two-year study of surgical rates and indices in rural Africa. East Central Afr J Surg 2011;16(3). http://www.ajol.info/index.php/ecajs/article/view/74250. Accessed 15 Dec 2013. / Description of a method to track surgical rates, relative to CS rates.
    27. 鈥⒙燢ushner A, Groen RS, Kingham TP. Percentage of cesarean sections among total surgical procedures in sub-Saharan Africa: possible indicator of the overall adequacy of surgical care. World J Surg 2010; 34:2007鈥?8 / Description of a method to track surgical rates, relative to CS rates.
    28. Hughes CD, McClain CD, Hagander L, et al. Ratio of cesarean deliveries to total operations and surgeon nationality are potential proxies for surgical capacity in central Haiti. World J Surg. 2013;37:1526鈥?. CrossRef
    29. Debas HT, Gosselin R, McCord C, Thind A. Surgery. In: Jamison DT, Breman JG, Measham AR, et al., editors. Disease control priorities in developing countries, vol. 2. New York: The World Bank/Oxford University Press; 2006. p. 1245鈥?0.
    30. Murray CJ, Vos T, Lozano R, et al. Disability adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990鈥?010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2010;380:2197鈥?23. CrossRef
    31. 鈥⑩€⒙燝rimes CE, Henry JA, Maraka J et al. Cost effectiveness of surgery in low- and middle-income countries: a systematic review. World J Surg 2014;38:252鈥?63. / Systematic review to describe the cost effectiveness of surgery.
    32. 鈥⑩€⒙燤erry AF, Cooper JB, Soyannwo O et al. International standards for a safe practice of anesthesia 2010. Can J Anesth 2010;57:1027鈥?4 / Defines minimum standards for provision of safe anesthesia at different levels of the hospital.
    33. WHO Guidelines for Safe Surgery (2009) Safe Surgery Saves Lives. WHO Press: World Health Organization, Geneva. http://whqlibdoc.who.int/publications/2009/9789241598552_eng.pdf. Accessed 15 Dec 2013.
    34. Hodges SC, Mijumbi C, Okello M, et al. Anaesthesia services in developing countries: defining the problems. Anaesthesia. 2007;62:4鈥?1. CrossRef
    35. WHO. Emergency and essential surgical care. Quality and safety tools. http://www.who.int/surgery/publications/immesc_quality_tools/en/index.html. Accessed 15 Dec 2013.
    36. Choo S, Perry H, Hesse AA, et al. Assessment of capacity for surgery, obstetrics and anaesthesia in 17 Ghanaian hospitals using a WHO assessment tool. Trop Med Int Health. 2010;15:1109鈥?5.
    37. Sherman L, Clement PT, Cherian MN, et al. Implementing Liberia鈥檚 poverty reduction strategy: an assessment of emergency and essential surgical care. Arch Surg. 2011;146:35鈥?. CrossRef
    38. Notrica MR, Evans FM, Knowlton LM, Kelly McQueen KA. Rwandan surgical and anesthesia infrastructure: a survey of district hospitals. World J Surg. 2011;35:1770鈥?0. CrossRef
    39. Spiegel DA, Choo S, Cherian M, et al. Quantifying surgical and anesthetic availability at primary health facilities in Mongolia. World J Surg. 2011;35:272鈥?. CrossRef
    40. Linden AF, Sekidde FS, Galukande M, et al. Challenges of surgery in developing countries: a survey of surgical and anesthesia capacity in Uganda鈥檚 public hospitals. World J Surg. 2012;36:1056鈥?5. CrossRef
    41. Chao TE, Burdic M, Ganjawalla K, et al. Survey of surgery and anesthesia infrastructure in Ethiopia. World J Surg. 2012;36:2545鈥?3. CrossRef
    42. Solis C, Le贸n P, Sanchez N, et al. Nicaraguan surgical and anesthesia infrastructure: survey of Ministry of Health hospitals. World J Surg. 2013;37:2109鈥?1. CrossRef
    43. Lebrun DG, Dhar D, Sarkar MI, et al. Measuring global surgical disparities: a survey of surgical and anesthesia infrastructure in Bangladesh. World J Surg. 2013;37:24鈥?1. CrossRef
    44. Vo D, Cherian MN, Bianchi S et al. Anesthesia capacity in 22 low and middle income countries. J Anesth Clin Res 2012;3:4. doi:10.4172/2155-6148.1000207 .
    45. Hoyler M, Leon P, Sanchez, et al. Nicaraguan surgical and anesthesia infrastructure: survey of Ministry of Health hospitals. World J Surg. 2013;37:2109鈥?2. CrossRef
    46. Bowman KG, Jovic G, Rangel S, Berry WR, Gawande AA. Pediatric emergency and essential surgical care in Zambian hospitals: a nationwide study. J Pediatr Surg. 2013;48:1363鈥?0. CrossRef
    47. Groen RS, Kamara TB, Dixon-Cole R, et al. A tool and index to assess surgical capacity in low income countries: an initial implementation in Sierra Leone. World J Surg. 2012;36:1970鈥?. CrossRef
    48. Henry JA, Windapo O, Kushner AL, Groen RS, Nwomeh BC. A survey of surgical capacity in rural southern Nigeria: opportunities for change. World J Surg. 2012;36:2811鈥?. CrossRef
    49. Kushner A, Groen RS, Kamar TB, et al. Assessment of pediatric surgery capacity at Government Hospitals in Sierra Leone. World J Surg. 2012;36:2554鈥?. CrossRef
    50. Jochberger S, Ismailova F, Lederer W, et al. Anesthesia and its allied disciplines in the developing world: a nationwide survey of the Republic of Zambia. Anesth Analg. 2008;106:942鈥?. CrossRef
    51. Jochberger S, Bataar O, Mendsaikhan N, et al. Anesthesia care in a medium-developed country: a nationwide survey of Mongolia. J Clin Anesth. 2010;22:443鈥?. CrossRef
    52. Size M, Soyannwo OA, Justins DM, et al. Pain management in developing countries. Anaesthesia. 2007;62(suppl 1):38鈥?3. CrossRef
    53. 鈥⒙燜unk LM, Weiser TG, Berry WR et al. Global operating theatre distribution and pulse oximetry supply: an estimation from reported data. Lancet. 2010;376:1055鈥?1 / Estimation of global need in terms of surgical and anesthesia workforce and infrastructure.
    54. Hoyler M, Finlayson SR, McClain CD et al. Shortage of doctors, shortage of data: a review of the global surgery, obstetrics, and anesthesia workforce literature. World J Surg. 2014;38:269鈥?0.
    55. Chen L, Evans T, Anand S, et al. Human resources for health: overcoming the crisis. Lancet. 2004;364:1984鈥?0. CrossRef
    56. Hongoro C, McPake B. How to bridge the gap in human resources for health. Lancet. 2004;364:1451鈥?. CrossRef
    57. Anand S, B盲rnighausen T. Human resources and health outcomes: cross-country econometric study. Lancet. 2004;364:1603鈥?. CrossRef
    58. Kruk ME, Wladis A, Mbembati N, et al. Human resource and funding constraints for essential surgery in district hospitals in Africa: a retrospective cross-sectional survey. PLoS Med. 2010;7:e1000242. doi:10.1371/journal.pmed.1000242 . CrossRef
    59. Ferrinho P, Sidat M, Goma F, Dussault G. Task-shifting: experiences and opinions of health workers in Mozambique and Zambia. Human Resour Health. 2012;10:34. CrossRef
    60. The World Bank. Health Expenditure per capita (current US$). http://data.worldbank.org/indicator/SH.XPD.PCAP. Accessed 15 Dec 2013.
    61. United Nations. Health in the post-2015 Development Agenda. http://www.worldwewant2015.org/health. Accessed 15 Dec 2013.
    62. 鈥⒙燤eara JG, Hagander L, Leather AJ. Surgery and global health: a Lancet Commission. Lancet 2014;383:12鈥?3. / Description of priority areas to improve access to safe surgery and anesthesia.
    63. Disease Control Priorities Project http://www.dcp2.org/page/main/Home.html. Accessed 15 Dec 2013.
    64. Mock C, Cherian M, Juillard C. Developing priorities for addressing surgical conditions globally: furthering the link between surgery and public health policy. World J Surg. 2010;34:381鈥?. CrossRef
    65. Gosselin R, Ozgediz D, Poenaru D. A square peg in a round hole? Challenges with DALY-based 鈥樷€楤urden of Disease鈥欌€?calculations in surgery and a call for alternative metrics. World J Surg. 2013;13:2507鈥?1. CrossRef
    66. 鈥⒙燦ewton M, Bird P. Impact of parallel anesthesia and surgical provider training in sub-Saharan Africa: a model for a resource-poor setting. World J Surg. 2010;34:445鈥?2 / Description of a successful nurse anesthesia training program, linked to a sustained increase in surgical activity.
    67. 鈥⒙燱hitaker DK, Walker I. College supports Uganda Fellowship Programme. Bull Roy Coll Anaesth 2012;73:43鈥? http://rcoa.ac.uk/system/files/CSQ-Bulletin73_0.pdf. Accessed 15 Dec 2013. / Description of successful institutional partnerships.
    68. 鈥⒙燣ipnick M, Mijumbi C, Dubowitz G et al. Surgery and anesthesia capacity-building in resource-poor settings: description of an ongoing academic partnership in Uganda. World J Surg. 2013;37:488鈥?7 / Description of successful institutional partnerships.
    69. AAGBI. The SAFE obstetric anaesthesia course. http://www.aagbi.org/international/international-relations-committee/refresher-courses. Accessed 15 Dec 2013.
    70. 鈥⒙燙anadian Anaesthesiologists鈥?Society International Education Foundation (CASIEF) Mission in Rwanda https://www.cas.ca/English/CASIEF-Rwanda. Accessed 15 Dec 2013. / Description of successful institutional partnerships.
    71. 鈥⒙燢innear JA, Bould MD, Ismailova F, Measures E. A new partnership for anesthesia training in Zambia: reflections on the first year. Can J Anaesth. 2013;60:484鈥?1 / Description of successful institutional partnerships.
    72. International Organization for Standardization. ISO 8835-7:2011. Inhalational anaesthesia systems鈥攑art 7: Anaesthetic systems for use in areas with limited logistical supplies of electricity and anaesthetic gases. www.iso.org. Accessed 15 Dec 2013.
    73. Duke T, Graham SM, Cherian MN, et al. Oxygen is an essential medicine: a call for international action. Int J Tuberc Lung Dis. 2010;14:1362鈥?.
    74. Dubowitz G, Breyer K, Lipnick M, Sall JW, Feiner J, Ikeda K, Bickler PE. Accuracy of the Lifebox pulse oximeter during hypoxia in healthy volunteers. Anaesthesia. 2013;68(12):1220鈥?. CrossRef
    75. Ansermino JM. Universal access to essential vital signs monitoring October. Anesth Analg. 2013;117:883鈥?. CrossRef
    76. WHO Model lists of essential medicines http://www.who.int/medicines/publications/essentialmedicines/en/. Accessed 15 Dec 2013.
    77. Funk LM, Conley DM, Berry WR, Gawande AA. Hospital management practices and availability of surgery in sub-Saharan Africa: a pilot study of three hospitals. World J Surg. 2013;37:2520鈥?. CrossRef
    78. Parry EHO, Percy DB. Anaesthesia and hospital links: supporting healthcare through South鈥揘orth hospital partnerships. Anaesthesia. 2007;62(suppl 1):11鈥?.
    79. UK Government. All parliamentary group on global health. improving health at home and abroad. How overseas volunteering from the NHS benefits the UK and the world. 2013. www.appg-globalhealth.org.uk. Accessed 15 Dec 2013.
    80. 鈥⑩€⒙燬rofenyoh E, Ivester T, Engmann C et al. Enhancing obstetric and neonatal care in a regional hospital in Ghana via continuous quality improvement. Int J Gyn Obstr 2012;116:17鈥?1 / Description of successful institutional partnerships inked to a quality improvement program.
    81. Bashford T. Quality improvement in low resource settings: an Ethiopian experience. Br J Hosp Med. 2013;74:286鈥?.
    82. Patel PB, Hoyler M, Maine R, et al. An opportunity for diagonal development in global surgery: cleft lip and palate care in resource-limited settings. Plast Surg Int. 2012;2012:892437. doi:10.1155/2012/892437 .
    83. Haynes AB, Weiser TG, Berry WR, et al. Safe Surgery Saves Lives Study Group. A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med. 2009;360:491鈥?. CrossRef
    84. Kwok AC, Funk LM, Baltaga R, et al. Implementation of the World Health Organization surgical safety checklist, including introduction of pulse oximetry, in a resource-limited setting. Ann Surg. 2013;257:633鈥?. CrossRef
    85. Yuan CT, Walsh D, Tomarken JL, et al. Incorporating the World Health Organization Surgical Safety Checklist into practice at two hospitals in Liberia. J Comm J Qual Patient Saf. 2012;38:254鈥?0.
    86. Russ S, Rout S, Sevdalis N, et al. Do safety checklists improve teamwork and communication in the operating theatre? A systematic review. Ann Surg. 2013;258:856鈥?1. CrossRef
    87. van Klei WA, Hoff RG, van Aarnhem EE, et al. Effects of the introduction of the WHO 鈥淪urgical Safety Checklist鈥?on in-hospital mortality: a cohort study. Ann Surg. 2012;255:44鈥?. CrossRef
    88. Vats A, Vincent CA, Nagpal K, et al. Practical challenges of introducing WHO surgical checklist: UK pilot experience. BMJ. 2010;340:b5433. doi:10.1136/bmj.b5433 . CrossRef
    89. Pickering SP, Robertson ER, Griffin D, et al. Compliance and use of the World Health Organization checklist in UK operating theatres. Br J Surg. 2013;100:1664鈥?0.
    90. Aveling EL, McCulloch P, Dixon-Woods M. A qualitative study comparing experiences of the surgical safety checklist in hospitals in high-income and low-income countries. BMJ Open. 2013;3:e003039. doi:10.1136/bmjopen-2013-003039 . CrossRef
  • 作者单位:Isabeau A. Walker (1)
    Tom Bashford (2)
    J. E. Fitzgerald (3)
    Iain H. Wilson (4)

    1. Department of Anaesthesia Great Ormond Street Hospital NHS Foundation Trust, UCL Institute of Child Health, Great Ormond Street, London, WC1N 3JH, UK
    2. Department of Anaesthesia, Cambridge University and Cambridge University Hospitals NHS, Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK
    3. Lifebox Foundation, 21 Portland Place, London, W1B 1PY, UK
    4. Department of Anaesthesia, Royal Devon and Exeter NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK
  • ISSN:2167-6275
文摘
Safe anesthesia is dependent on a skilled clinician, a functioning anesthesia machine, monitoring equipment, drugs and a healthcare facility with support services and staff. In high-income regions we expect a quality service with excellent levels of safety. In low-income countries, competition for healthcare resources is significant, and surgery has been neglected as a component of public health services. Anesthesia is relatively expensive because of the high cost of imported equipment and drugs, and underinvestment is common. Small numbers of inadequately resourced providers struggle to deliver a service sometimes associated with alarmingly high mortality rates (as much as 1,000 times higher than in the best centers). These factors impact on development of the specialty and recruitment and training, creating a dangerous situation for patients. We review published data on anesthesia services in low-income regions, describe the difficulties, analyze where improvements should be prioritized and make recommendations to improve anesthesia safety in poorer regions of the world.

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