TG13 flowchart for the management of acute cholangitis and cholecystitis
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  • 作者:Fumihiko Miura (1)
    Tadahiro Takada (1)
    Steven M. Strasberg (2)
    Joseph S. Solomkin (3)
    Henry A. Pitt (4)
    Dirk J. Gouma (5)
    O. James Garden (6)
    Markus W. Büchler (7)
    Masahiro Yoshida (8)
    Toshihiko Mayumi (9)
    Kohji Okamoto (10)
    Harumi Gomi (11)
    Shinya Kusachi (12)
    Seiki Kiriyama (13)
    Masamichi Yokoe (14)
    Yasutoshi Kimura (15)
    Ryota Higuchi (16)
    Yuichi Yamashita (17)
    John A. Windsor (18)
    Toshio Tsuyuguchi (19)
    Toshifumi Gabata (20)
    Takao Itoi (21)
    Jiro Hata (22)
    Kui-Hin Liau (23)
  • 关键词:Acute cholangitis ; Acute cholecystitis ; Biliary drainage ; Laparoscopic cholecystectomy ; Guidelines
  • 刊名:Journal of Hepato-Biliary-Pancreatic Sciences
  • 出版年:2013
  • 出版时间:January 2013
  • 年:2013
  • 卷:20
  • 期:1
  • 页码:47-54
  • 全文大小:482KB
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    9. Kiriyama S, Takada T, Strasberg SM, Solomkin JS, Mayumi T, Pitt HA, et al. New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo guidelines. J Hepatobiliary Pancreat Sci. 2012;19:548-6. <a class="external" href="http://dx.doi.org/10.1007/s00534-012-0537-3">CrossRefa>
    10. Tsuyuguchi T, Sugiyama H, Sakai Y, Nishikawa T, Yokosuka O, Mayumi T, et al. Prognostic factors of acute cholangitis in cases managed using the Tokyo Guidelines. J Hepatobiliary Pancreat Sci. 2012;19:557-5. <a class="external" href="http://dx.doi.org/10.1007/s00534-012-0538-2">CrossRefa>
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    14. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble WT, Marshall JC, Bion J, et al. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med. 2010;38:367-4. <a class="external" href="http://dx.doi.org/10.1097/CCM.0b013e3181cb0cdc">CrossRefa>
    15. Ferrer R, Artigas A, Levy MM, Blanco J, Gonzalez-Diaz G, Garnacho-Montero J, et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA. 2008;299:2294-03. <a class="external" href="http://dx.doi.org/10.1001/jama.299.19.2294">CrossRefa>
    16. El Solh AA, Akinnusi ME, Alsawalha LN, Pineda LA. Outcome of septic shock in older adults after implementation of the sepsis “bundle- J Am Geriatr Soc. 2008;56:272-. <a class="external" href="http://dx.doi.org/10.1111/j.1532-5415.2007.01529.x">CrossRefa>
    17. Nguyen HB, Corbett SW, Steele R, Banta J, Clark RT, Hayes SR, et al. Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality. Crit Care Med. 2007;35:1105-2. <a class="external" href="http://dx.doi.org/10.1097/01.CCM.0000259463.33848.3D">CrossRefa>
    18. Eskelinen M, Ikonen J, Lipponen P. Diagnostic approaches in acute cholecystitis; a prospective study of 1333 patients with acute abdominal pain. Theor Surg. 1993;8:15-0.
    19. Staniland JR, Ditchburn J, De Dombal FT. Clinical presentation of acute abdomen: study of 600 patients. Br Med J. 1972;3:393-. <a class="external" href="http://dx.doi.org/10.1136/bmj.3.5823.393">CrossRefa>
    20. Trowbridge RL, Rutkowski NK, Shojania KG. Does this patient have acute cholecystitis? JAMA. 2003;289:80-. <a class="external" href="http://dx.doi.org/10.1001/jama.289.1.80">CrossRefa>
    21. Hirota M, Takada T, Kawarada Y, Nimura Y, Miura F, Hirata K, et al. Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:78-2. (clinical practice guidelines: CPGs). <a class="external" href="http://dx.doi.org/10.1007/s00534-006-1159-4">CrossRefa>
    22. Ralls PW, Halls J, Lapin SA, Quinn MF, Morris UL, Boswell W. Prospective evaluation of the sonographic Murphy sign in suspected acute cholecystitis. J Clin Ultrasound. 1982;10:113-. <a class="external" href="http://dx.doi.org/10.1002/jcu.1870100305">CrossRefa>
    23. Soyer P, Brouland JP, Boudiaf M, Kardache M, Pelage JP, Panis Y, et al. Color velocity imaging and power Doppler sonography of the gallbladder wall: a new look at sonographic diagnosis of acute cholecystitis. AJR Am J Roentgenol. 1998;171:183-.
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    27. Noble VE, Liteplo AS, Nelson BP, Thomas SH. The impact of analgesia on the diagnostic accuracy of the sonographic Murphy’s sign. Eur J Emerg Med. 2010;17:80-. <a class="external" href="http://dx.doi.org/10.1097/MEJ.0b013e32832e9627">CrossRefa>
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    29. Kumar A, Deed JS, Bhasin B, Thomas S. Comparison of the effect of diclofenac with hyoscine- / N-butylbromide in the symptomatic treatment of acute biliary colic. Aust NZ J Surg. 2004;74:573-. <a class="external" href="http://dx.doi.org/10.1111/j.1445-2197.2004.03058.x">CrossRefa>
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    31. Sugiyama M, Tokuhara M, Atomi Y. Is percutaneous cholecystostomy the optimal treatment for acute cholecystitis in the very elderly? World J Surg. 1998;22:459-3. <a class="external" href="http://dx.doi.org/10.1007/s002689900416">CrossRefa>
    32. Chopra S, Dodd GD 3rd, Mumbower AL, Chintapalli KN, Schwesinger WH, Sirinek KR, et al. Treatment of acute cholecystitis in non-critically ill patients at high surgical risk: comparison of clinical outcomes after gallbladder aspiration and after percutaneous cholecystostomy. AJR Am J Roentgenol. 2001;176:1025-1.
    33. Yokoe M, Takada T, Strasberg SM, Solomkin JS, Mayumi T, Gomi H, et al. New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo guidelines. J Hepatobiliary Pancreat Sci. 2012;19:578-5. <a class="external" href="http://dx.doi.org/10.1007/s00534-012-0548-0">CrossRefa>
    34. Inui K, Nakazawa S, Naito Y, Kimoto E, Yamao K. Nonsurgical treatment of cholecystolithiasis with percutaneous transhepatic cholecystoscopy. Am J Gastroenterol. 1988;83:1124-.
    35. Boland GW, Lee MJ, Mueller PR, Dawson SL, Gaa J, Lu DS, et al. Gallstones in critically ill patients with acute calculous cholecystitis treated by percutaneous cholecystostomy: nonsurgical therapeutic options. AJR Am J Roentgenol. 1994;162:1101-.
    36. Majeed AW, Reed MW, Ross B, Peacock J, Johnson AG. Gallstone removal with a modified cholecystoscope: an alternative to cholecystectomy in the high-risk patient. J Am Coll Surg. 1997;184:273-0.
    37. Shirai Y, Tsukada K, Kawaguchi H, Ohtani T, Muto T, Hatakeyama K. Percutaneous transhepatic cholecystostomy for acute acalculous cholecystitis. Br J Surg. 1993;80:1440-. <a class="external" href="http://dx.doi.org/10.1002/bjs.1800801129">CrossRefa>
  • 作者单位:Fumihiko Miura (1)
    Tadahiro Takada (1)
    Steven M. Strasberg (2)
    Joseph S. Solomkin (3)
    Henry A. Pitt (4)
    Dirk J. Gouma (5)
    O. James Garden (6)
    Markus W. Büchler (7)
    Masahiro Yoshida (8)
    Toshihiko Mayumi (9)
    Kohji Okamoto (10)
    Harumi Gomi (11)
    Shinya Kusachi (12)
    Seiki Kiriyama (13)
    Masamichi Yokoe (14)
    Yasutoshi Kimura (15)
    Ryota Higuchi (16)
    Yuichi Yamashita (17)
    John A. Windsor (18)
    Toshio Tsuyuguchi (19)
    Toshifumi Gabata (20)
    Takao Itoi (21)
    Jiro Hata (22)
    Kui-Hin Liau (23)

    1. Department of Surgery, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8605, Japan
    2. Section of Hepatobiliary and Pancreatic Surgery, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA
    3. Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    4. Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    5. Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    6. Clinical Surgery, The University of Edinburgh, Edinburgh, UK
    7. Department of Surgery, University of Heidelberg, Heidelberg, Germany
    8. Clinical Research Center Kaken Hospital, International University of Health and Welfare, Ichikawa, Japan
    9. Department of Emergency and Critical Care Medicine, Ichinomiya Municipal Hospital, Ichinomiya, Japan
    10. Department of Surgery, Kitakyushu Municipal Yahata Hospital, Kitakyushu, Japan
    11. Center for Clinical Infectious Diseases, Jichi Medical University, Shimotsuke, Tochigi, Japan
    12. Department of Surgery, Toho University Medical Center Ohashi Hospital, Tokyo, Japan
    13. Department of Gastroenterology, Ogaki Municipal Hospital, Ogaki, Japan
    14. General Internal Medicine, Nagoya Daini Red Cross Hospital, Nagoya, Japan
    15. Department of Surgical Oncology and Gastroenterological Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan
    16. Department of Surgery, Institute of Gastroenterology, Tokyo Women’s Medical University, Tokyo, Japan
    17. Department of Gastroenterological Surgery, Fukuoka University School of Medicine, Fukuoka, Japan
    18. Department of Surgery, The University of Auckland, Auckland, New Zealand
    19. Department of Medicine and Clinical Oncology, Graduate School of Medicine Chiba University, Chiba, Japan
    20. Department of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    21. Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
    22. Department of Endoscopy and Ultrasound, Kawasaki Medical School, Okayama, Japan
    23. Hepatobiliary and Pancreatic Surgery, Nexus Surgical Associates, Mount Elizabeth Hospital, Singapore, Singapore
文摘
We propose a management strategy for acute cholangitis and cholecystitis according to the severity assessment. For Grade I (mild) acute cholangitis, initial medical treatment including the use of antimicrobial agents may be sufficient for most cases. For non-responders to initial medical treatment, biliary drainage should be considered. For Grade II (moderate) acute cholangitis, early biliary drainage should be performed along with the administration of antibiotics. For Grade III (severe) acute cholangitis, appropriate organ support is required. After hemodynamic stabilization has been achieved, urgent endoscopic or percutaneous transhepatic biliary drainage should be performed. In patients with Grade II (moderate) and Grade III (severe) acute cholangitis, treatment for the underlying etiology including endoscopic, percutaneous, or surgical treatment should be performed after the patient’s general condition has been improved. In patients with Grade I (mild) acute cholangitis, treatment for etiology such as endoscopic sphincterotomy for choledocholithiasis might be performed simultaneously, if possible, with biliary drainage. Early laparoscopic cholecystectomy is the first-line treatment in patients with Grade I (mild) acute cholecystitis while in patients with Grade II (moderate) acute cholecystitis, delayed/elective laparoscopic cholecystectomy after initial medical treatment with antimicrobial agent is the first-line treatment. In non-responders to initial medical treatment, gallbladder drainage should be considered. In patients with Grade III (severe) acute cholecystitis, appropriate organ support in addition to initial medical treatment is necessary. Urgent or early gallbladder drainage is recommended. Elective cholecystectomy can be performed after the improvement of the acute inflammatory process. Free full-text articles and a mobile application of TG13 are available via http://www.jshbps.jp/en/guideline/tg13.html.

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