Biodistribution and Radiation Dosimetry of the Enterobacteriaceae-Specific Imaging Probe [¹⁸F]Fluorodeoxysorbitol Determined by PET/CT in Healthy Human Volunteers

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• 作者：Wenjia Zhu ; Shaobo Yao ; Haiqun Xing ; Hui Zhang…
• 关键词：Key words[18F] FDS ; Biodistribution ; Radiation dosimetry ; Enterobacteriaceae ; PET
• 刊名：Molecular Imaging and Biology
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：18
• 期：5
• 页码：782-787
• 全文大小：779 KB
• 刊物主题：Imaging / Radiology;
• 出版者：Springer US
• ISSN：1860-2002
• 卷排序：18

文摘

Purpose[18F]fluorodeoxysorbitol ([18F]FDS) is the first radiopharmaceutical specific for a category of bacteria and has the potential to specifically detect Enterobacteriaceae infections. The purpose of this study was to testify the safety and investigate the biodistribution and radiation dosimetry of [18F]FDS in healthy human bodies.