The effect of age on survival and quality of life in elderly head and neck cancer patients: a long-term prospective study

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• 作者：Marc P. van der Schroeff ; Wynia Derks ; Gerrit Jan Hordijk and Rob J. de Leeuw
• 关键词：Age ; Survival ; Quality of life ; Head and neck cancer
• 刊名：European Archives of Oto-Rhino-Laryngology
• 出版年：2007
• 出版时间：April, 2007
• 年：2007
• 卷：264
• 期：4
• 页码：415-422
• 全文大小：361 KB

文摘

Little is known about long-term treatment outcome of elderly head and neck cancer patients and their quality of life (QOL). One hundred and eighteen older (≥70 years) and 148 younger (45–60 years) patients with head and neck cancer were followed up for 3–6 years. In the long-term follow-up 33 younger and 24 older patients completed the EORTC QLQ-C30 and H&N35 and a questionnaire about depression. The survival rate after 3–6 years for younger patients was 36 % , as compared to 31 % in the older patient group. Higher tumour stages, more co-morbidity and non-standard treatment showed to be independent prognostic factors for mortality. No independent prognostic value of age could be found. The global QOL score remains roughly comparable. Even up to 6 years after treatment, we found no significant differences in survival or overall QOL between older and younger head and neck cancer patients.