Diagnostic values of serum cathepsin B and D in patients with nasopharyngeal carcinoma

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• 作者：Gongjun Tan ; Qianxu Liu ; Xiaowei Tang ; Ting Kang ; Yuejin Li ; Jinping Lu…
• 关键词：Biomarker ; Diagnostic value ; Nasopharyngeal carcinoma ; Cathepsin B ; Cathepsin D
• 刊名：BMC Cancer
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：480 KB
• 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2407

文摘

Background The diagnostic and prognostic significance of increased cathepsin B (CTSB) and cathepsin D (CTSD) concentration in the serum of cancer patients were evaluated for some tumor types. High expression of CTSD and CTSB was detected in biopsy tissues from nasopharyngeal carcinoma (NPC). However, whether CTSD and CTSB serve as diagnostic and prognostic markers of NPC remains unclear.