Methylation-associated Has-miR-9 deregulation in paclitaxel- resistant epithelial ovarian carcinoma
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- 作者：Xiao Li ; Qianqian Pan ; Xiaoyun Wan ; Yuyan Mao ; Weiguo Lu ; Xing Xie…
- 关键词：Ovarian carcinoma ; Chemoresistance ; miR ; 9 ; Methylation
- 刊名：BMC Cancer
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：15
- 期：1
- 全文大小：1,699 KB
- 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1471-2407
文摘
Background Drug resistance is still one of the key causes of death in epithelial ovarian carcinoma (EOC) patients, however there are very few strategies to reverse chemoresistance. Here we try to clarify whether and how miR-9 takes part in the regulation of paclitaxel sensitivity.