Effect of TRPC6 knockdown on puromycin aminonucleoside-induced podocyte injury
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- 作者：Xifeng Sun (1) (2)
Yongli Chu (3)
Chun Zhang (1)
Xiyun Du (2)
Fangfang He (1)
Shan Chen (1)
Pan Gao (1)
Jianshe Liu (1)
Zhonghua Zhu (1)
Xianfang Meng (4) - 关键词：TRPC6 ; puromycin aminonucleoside ; podocyte ; permeability ; cytoskeleton
- 刊名：Journal of Huazhong University of Science and Technology [Medical Sciences]
- 出版年：2012
- 出版时间：June 2012
- 年：2012
- 卷：32
- 期：3
- 页码：340-345
- 全文大小：547KB
- 参考文献：1. Liakopoulos V, Huerta A, Cohen S, / et al. Familial collapsing focal segmental glomerulosclerosis. Clin Nephrol, 2011,75(4):362-68
2. Winn MP, Conlon PJ, Lynn KL, / et al. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science, 2005,308(5729):1801-804 CrossRef
3. Reiser J, Polu KR, Moller CC, / et al. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet, 2005,37(7):739-44 CrossRef
4. Eckel J, Lavin PJ, Finch EA, / et al. TRPC6 enhances angiotensin II-induced albuminuria. Am Soc Nephrol, 2011,22(3):526-35 CrossRef
5. Moller CC, Wei C, Altintas MM, / et al. Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol, 2007,18(1):29-6 CrossRef
6. Jiang HJ, Chang Y, Zhu ZH, / et al. Role of CD2-associated protein in podocyte differentiation. Sheng Li Xue Bao (Chinese), 2008,60(1):135-42
7. Zhang C, Jiang HJ, Chang Y, / et al. Downregulation of CD2-associated protein impaired the physiological functions of podocytes. Cell Biol Int, 2009,33(6):632-39 CrossRef
8. Li X, Yuan H, Zhang X. Adriamycin increases podocyte permeability: evidence and molecular mechanism. Chin Med J, 2003,116(12):1831-835
9. Elbashir SM, Harborth J, Lendeckel W, / et al. Duplexes of 21 nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 2001,411(6836):494-98 CrossRef
10. Brummelkamp TR, Bemards R, Agami R, / et al. A system for stable expression of short interfering RNAi in mammalan cells. Science, 2002,296(5567):550-53 CrossRef
11. Kim YH, Goyal M, Kurnit D / et al. Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat. Kidney Int, 2001,60(3):957-68 CrossRef
12. Wen D, You L, Zhang Q, / et al. Upregulation of nestin protects podocytes from apoptosis induced by puromycin aminonucleoside. Am J Nephrol, 2011,34(5):423-34 CrossRef
13. Reiser J, Oh J, Shirato I, / et al. Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem, 2004, 279(33):34827-4832 CrossRef
14. Hunt JL, Pollak MR, Denker BM, / et al. Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation. J Am Soc Nephrol, 2005,16(6):1593-602 CrossRef
15. Sun X, Fang Z, Zhu Z, / et al. Effect of Down-regulation of TRPC6 on puromycin aminonucleoside-induced apoptosis of mouse podocyte. J Huazhong Univ Sci Technolog [Med Sci], 2009,29(4):417-22 CrossRef
16. Kanplan J, Kim S, North K, / et al. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis. Nat Genet, 2000,24(3):251-56 CrossRef
17. Zhang C, Jiang H, Chang Y, / et al. Knocking-down CD2AP gene expression inhibits the proliferation and blocks the division of podocytes. Chin J Nephro (Chinese), 2007,23(12):778-83
18. Sun X, Zhang C, Fang Z, / et al. Effect of TRPC6 overexpression on slit diaphragm-associated molecules and cytoskeleton of podocytes in mouse. Chin J Nepthrol (Chinese), 2009,25(7):519-21 - 作者单位：Xifeng Sun (1) (2)
Yongli Chu (3)
Chun Zhang (1)
Xiyun Du (2)
Fangfang He (1)
Shan Chen (1)
Pan Gao (1)
Jianshe Liu (1)
Zhonghua Zhu (1)
Xianfang Meng (4)
1. Department of Nephrology, Union Hospital, Tongji Medical College, Huangzhong University of Science and Technology, Wuhan, 430022, China
2. Department of Nephrology, Zibo Central Hospital, Zibo, 255036, China
3. Department of Obstetrics and Gynecology, Yantai Yuhuangding Hospital, Qingdao University Medical School, Yantai, 264000, China
4. Department of Neurobiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
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