Therapeutic effects of histone deacetylase inhibitors in a murine asthma model

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• 作者：Yuan Ren ; Xinming Su ; Lingfei Kong ; Menglu Li ; Xuan Zhao ; Na Yu…
• 关键词：Bronchial asthma ; Histone deacetylase ; Airway inflammation ; Airway hyperresponsiveness
• 刊名：Inflammation Research
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：65
• 期：12
• 页码：995-1008
• 全文大小：27,989 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Immunology
  Pharmacology and Toxicology
  Allergology
  Dermatology
  Neurology
  Rheumatology
  
• 出版者：Birkh盲user Basel
• ISSN：1420-908X
• 卷排序：65

文摘

Objective and designTo investigate the therapeutic effects of various HDAC inhibitors on the development of chronic allergic airway disease in mice with airway inflammation, airway remodeling, and airway hyperresponsiveness.