Fibrillary glomerulonephritis complicated by membranous nephropathy in a patient with tuberculosis

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• 作者：Xueguang Liu (1)
  Hong Liu (2)
  Zhonghua Zhao (1)
  Zhigang Zhang (1)
  Xiaoqiang Ding (2)
  
• 关键词：Fibrillary glomerulonephritis ; Membranous nephropathy ; Electron microscopy ; Tuberculosis
• 刊名：International Urology and Nephrology
• 出版年：2013
• 出版时间：October 2013
• 年：2013
• 卷：45
• 期：5
• 页码：1501-1504
• 全文大小：271KB
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  7. Bhat ZY, Zeng X, Hingorani J, Khan S, Mohanty MJ (2011) Fibrillary glomerulonephritis in a patient with systemic lupus erythematosus: a rare association. Int Urol Nephrol 19. doi: 10.1007/s11255-011-0073-0
  8. Yuan Q, Sun L, Feng J, Liu N, Jiang Y, Ma J, Wang L (2010) Lumbar tuberculosis associated with membranous nephropathy and interstitial nephritis. J Clin Microbiol 48(6):2303鈥?306 CrossRef
  9. Collins M, Navaneethan SD, Chung M, Sloand J, Goldman B, Appel G, Rovin BH (2008) Rituximab treatment of fibrillary glomerulonephrit. Am J Kidney Dis 52(6):1158鈥?162 CrossRef
  
• 作者单位：Xueguang Liu (1)
  Hong Liu (2)
  Zhonghua Zhao (1)
  Zhigang Zhang (1)
  Xiaoqiang Ding (2)
  
  1. Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, 200032, China
  2. Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China
  
• ISSN：1573-2584

文摘

Fibrillary glomerulonephritis (FGN) is a morphologically defined entity characterized by glomerular accumulations of non-branching, randomly arranged fibrils; these differ from amyloid fibrils by their larger size and lack of reactivity with Congo red and other amyloid-specific dyes. FGN is a rare disease and may mimic membranous nephropathy under routine light microscopy and immunohistochemistry. However, electron microscopy shows the fibrillary nature of these glomerular deposits. We report a rare case of membranous nephropathy complicated by fibrillary deposits in a 60-year-old man with a history of bone tuberculosis.