The association between C-159T polymorphism in CD14 gene and susceptibility to tuberculosis: a meta-analysis

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• 作者：Qing Yuan (1)
  Huifang Chen (1) (2)
  Xueyan Zheng (2)
  Xiaming Chen (1)
  Qun Li (1)
  Yanping Zhang (1)
  Xiaorong Zhang (1)
  Tingli Shi (2)
  Junhua Zhou (2)
  Qing Chen (2)
  Shouyi Yu (2)
  
• 关键词：Tuberculosis ; CD14 ; Polymorphism ; Meta ; analysis
• 刊名：Molecular Biology Reports
• 出版年：2014
• 出版时间：November 2014
• 年：2014
• 卷：41
• 期：11
• 页码：7623-7629
• 全文大小：489 KB
• 参考文献：1. The Lancet (2012) Tuberculosis control and elimination in 2012 and beyond. / Lancet 2012, 379:1076
  2. Lawn SD, Zumla AI (2011) Tuberculosis. Lancet 378:57-2 CrossRef
  3. WHO (2012) Global tuberculosis report 2012
  4. Druszczynska M, Kowalewicz-Kulbat M, Fol M, Wlodarczyk M, Rudnicka W (2012) Latent M. tuberculosis infection–pathogenesis, diagnosis, treatment and prevention strategies. Pol J Microbiol 61:3-0
  5. Ernst JD (2012) The immunological life cycle of tuberculosis. Nat Rev Immunol 12:581-91 CrossRef
  6. Axelsson-Robertson R, Magalhaes I, Parida SK, Zumla A, Maeurer M (2012) The immunological footprint of Mycobacterium tuberculosis T-cell epitope recognition. J Infect Dis 205(Suppl 2):S301–S315 CrossRef
  7. Azad AK, Sadee W, Schlesinger LS (2012) Innate immune gene polymorphisms in tuberculosis. Infect Immun 80:3343-359 CrossRef
  8. Alagarasu K, Selvaraj P, Swaminathan S, Raghavan S, Narendran G (2009) Narayanan PR: CCR2, MCP-1, SDF-1a & DC-SIGN gene polymorphisms in HIV-1 infected patients with & without tuberculosis. Indian J Med Res 130:444-50
  9. Bahari G, Hashemi M, Taheri M, Naderi M, Eskandari-Nasab E, Atabaki M (2012) Association of IRGM polymorphisms and susceptibility to pulmonary tuberculosis in Zahedan Southeast Iran. Sci World J 2012:950801
  10. Baker AR, Qiu F, Randhawa AK, Horne DJ, Adams MD, Shey M, Barnholtz-Sloan J, Mayanja-Kizza H, Kaplan G, Hanekom WA et al (2012) Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data. PLoS One 7:e47597 CrossRef
  11. Ben-Selma W, Ben-Kahla I, Boukadida J, Harizi H (2011) Contribution of the P2X7 1513A/C loss-of-function polymorphism to extrapulmonary tuberculosis susceptibility in Tunisian populations. FEMS Immunol Med Microbiol 63:65-2 CrossRef
  12. Hanta I, Tastemir-Korkmaz D, Demirhan O, Hanta D, Kuleci S, Seydaoglu G (2012) Association of the Nramp1 gene polymorphisms and clinical forms in patients with tuberculosis. Bratisl Lek Listy 113:657-60
  13. Mishra G, Poojary SS, Raj P, Tiwari PK (2012) Genetic polymorphisms of / CCL2, / CCL5, / CCR2 and / CCR5 genes in Sahariya tribe of North Central India: an association study with pulmonary tuberculosis. Infect Genet Evol 12:1120-127 CrossRef
  14. Peng R, Yue J, Han M, Zhao Y, Liu L, Liang L (2012) The IL-17F sequence variant is associated with susceptibility to tuberculosis. Gene 515:229-32 CrossRef
  15. Pydi SS, Sunder SR, Venkatasubramanian S, Kovvali S, Jonnalagada S, Valluri VL (2013) Killer cell immunoglobulin like receptor gene association with tuberculosis. Hum Immunol 74:85-2 CrossRef
  16. Zhang G, Zhou B, Wang W, Zhang M, Zhao Y, Wang Z, Yang L, Zhai J, Feng CG, Wang J, Chen X (2012) A functional single-nucleotide polymorphism in the promoter of the gene encoding interleukin 6 is associated with susceptibility to tuberculosis. J Infect Dis 205:1697-704 CrossRef
  17. Alavi-Naini R, Salimi S, Sharifi-Mood B, Davoodikia AA, Moody B, Naghavi A (2012) Association between the CD14 gene C-159T polymorphism and serum soluble CD14 with pulmonary tuberculosis. Int J Tuberc Lung Dis 16:1383-387 CrossRef
  18. Ayaslioglu E, Kalpaklioglu F, Kavut AB, Erturk A, Capan N, Birben E (2012) The role of CD14 gene promoter polymorphism in tuberculosis susceptibility. J Microbiol Immunol Infect 46:158-63 CrossRef
  19. Xue Y, Zhao ZQ, Chen F, Zhang L, Li GD, Ma KW, Bai XF, Zuo YJ (2012) Polymorphisms in the promoter of the CD14 gene and their ass
• 作者单位：Qing Yuan (1)
  Huifang Chen (1) (2)
  Xueyan Zheng (2)
  Xiaming Chen (1)
  Qun Li (1)
  Yanping Zhang (1)
  Xiaorong Zhang (1)
  Tingli Shi (2)
  Junhua Zhou (2)
  Qing Chen (2)
  Shouyi Yu (2)
  
  1. Songgang Health Inspection and Prevention Institute, Shenzhen, China
  2. Department of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, China
  
• ISSN：1573-4978

文摘

The association between CD14 gene C-159T polymorphism and tuberculosis (TB) susceptibility remains inconclusive. To derive a more precise estimation of the correlation, we performed a meta-analysis summarize the possible at a systematic manner. PubMed, HighWire and ScienceDirect databases covering all papers (up to November 2012) were searched. Statistical analyses were conducted by Rev-Man and STATA. Random- and fixed-effect models were used to estimate pooled odds ratios (ORs) and 95?% confidence intervals (CIs), based on between-study heterogeneity. Eight published case–control studies investigating the relationship between C-159T polymorphism in CD14 gene and TB susceptibility were included. Results showed that individuals with T allele have an increased risk of TB compared with those with C allele (OR (95?% CI) was 1.52 (1.11, 2.08) for TT vs. TC?+?CC, P?P?=?0.04). When stratified by ethnicity, variant TT homozygote carriers had an 86?% increased risk of TB in Asians (OR (95?% CI) was 1.86 (1.57, 2.20) for TT vs. TC?+?CC, P?P?=?0.61). This meta-analysis suggests that C-159T polymorphism in CD14 gene is associated with increased risk of TB, especially in Asians, but not in Caucasians.