Maternal lifestyle factors in pregnancy and congenital heart defects in offspring: review of the current evidence

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• 作者：Yu Feng (1)
  Di Yu (1)
  Lei Yang (1)
  Min Da (1)
  Zhiqi Wang (1)
  Yuan Lin (2)
  Bixian Ni (2)
  Song Wang (1)
  Xuming Mo (1)
  
  1. Department of Cardiothoracic Surgery ; The Affiliated Children鈥檚 Hospital of Nanjing Medical University ; Nanjing ; Jiangsu ; P.R. China
  2. Department of Epidemiology and Biostatistics ; Jiangsu Key Lab of Cancer Biomarkers ; Prevention and Treatment ; Cancer Center ; School of Public Health ; Nanjing Medical University ; Nanjing ; Jiangsu ; P.R. China
  
• 关键词：Congenital heart defects ; Maternal lifestyle factors ; Smoking ; BMI
• 刊名：Italian Journal of Pediatrics
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：40
• 期：1
• 全文大小：230 KB
• 参考文献：1. Rosamond, W, Flegal, K, Friday, G, Furie, K, Go, A, Greenlund, K, Haase, N, Ho, M, Howard, V, Kissela, B, Kittner, S, Lloyd-Jones, D, McDermott, M, Meigs, J, Moy, C, Nichol, G, O'Donnell, CJ, Roger, V, Rumsfeld, J, Sorlie, P, Steinberger, J, Thom, T, Wasserthiel-Smoller, S, Hong, Y (2007) Heart disease and stroke statistics鈥?007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115: pp. e69-e171 CrossRef
  2. Pierpont, ME, Basson, CT, Benson, DW, Gelb, BD, Giglia, TM, Goldmuntz, E, McGee, G, Sable, CA, Srivastava, D, Webb, CL (2007) Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation 115: pp. 3015-3038 CrossRef
  3. Gatzoulis, MA (2004) Adult congenital heart disease: a cardiovascular area of growth in urgent need of additional resource allocation. Int J Cardiol 97: pp. 1-2 CrossRef
  4. Bom, T, Zomer, AC, Zwinderman, AH, Meijboom, FJ, Bouma, BJ, Mulder, BJ (2011) The changing epidemiology of congenital heart disease. Nat Rev Cardiol 8: pp. 50-60 CrossRef
  5. Kavey, RE, Allada, V, Daniels, SR, Hayman, LL, McCrindle, BW, Newburger, JW, Parekh, RS, Steinberger, J (2006) Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation 114: pp. 2710-2738 CrossRef
  6. Wolf, M, Basson, CT (2010) The molecular genetics of congenital heart disease: a review of recent developments. Curr Opin Cardiol 25: pp. 192-197 CrossRef
  7. Jenkins, KJ, Correa, A, Feinstein, JA, Botto, L, Britt, AE, Daniels, SR, Elixson, M, Warnes, CA, Webb, CL (2007) Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation 115: pp. 2995-3014 CrossRef
  8. Kallen, K (1999) Maternal smoking and congenital heart defects. Eur J Epidemiol 15: pp. 731-737 CrossRef
  9. Hackshaw, A, Rodeck, C, Boniface, S (2011) Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 malformed cases and 11.7 million controls. Hum Reprod Update 17: pp. 589-604 CrossRef
  10. Lee, LJ, Lupo, PJ (2013) Maternal smoking during pregnancy and the risk of congenital heart defects in offspring: a systematic review and metaanalysis. Pediatr Cardiol 34: pp. 398-407 CrossRef
  11. Baardman, ME, Kerstjens-Frederikse, WS, Corpeleijn, E, Walle, HE, Hofstra, RM, Berger, RM, Bakker, MK (2012) Combined adverse effects of maternal smoking and high body mass index on heart development in offspring: evidence for interaction?. Heart 98: pp. 474-479 CrossRef
  12. Patel, SS, Burns, TL, Botto, LD, Riehle-Colarusso, TJ, Lin, AE, Shaw, GM, Romitti, PA (2012) Analysis of selected maternal exposures and non-syndromic atrioventricular septal defects in the National Birth Defects Prevention Study, 1997鈥?005. Am J Med Genet A 158A: pp. 2447-2455 CrossRef
  13. Carmichael, SL, Shaw, GM, Yang, W, Lammer, EJ (2003) Maternal periconceptional alcohol consumption and risk for conotruncal heart defects. Birth Defects Res A Clin Mol Teratol 67: pp. 875-878 CrossRef
  14. Grewal, J, Carmichael, SL, Ma, C, Lammer, EJ, Shaw, GM (2008) Maternal periconceptional smoking and alcohol consumption and risk for select congenital anomalies. Birth Defects Res A Clin Mol Teratol 82: pp. 519-526 CrossRef
  15. Strandberg-Larsen, K, Skov-Ettrup, LS, Gronbaek, M, Andersen, AM, Olsen, J, Tolstrup, J (2011) Maternal alcohol drinking pattern during pregnancy and the risk for an offspring with an isolated congenital heart defect and in particular a ventricular septal defect or an atrial septal defect. Birth Defects Res A Clin Mol Teratol 91: pp. 616-622 CrossRef
  16. Mateja, WA, Nelson, DB, Kroelinger, CD, Ruzek, S, Segal, J (2012) The association between maternal alcohol use and smoking in early pregnancy and congenital cardiac defects. J Womens Health (Larchmt) 21: pp. 26-34 CrossRef
  17. Liu, S, Joseph, KS, Lisonkova, S, Rouleau, J, Hof, M, Sauve, R, Kramer, MS (2013) Association between maternal chronic conditions and congenital heart defects: a population-based cohort study. Circulation 128: pp. 583-589 CrossRef
  18. O鈥橪eary, CM, Elliott, EJ, Nassar, N, Bower, C (2013) Exploring the potential to use data linkage for investigating the relationship between birth defects and prenatal alcohol exposure. Birth Defects Res A Clin Mol Teratol 97: pp. 497-504 CrossRef
  19. Kuciene, R, Dulskiene, V (2009) Maternal socioeconomic and lifestyle factors during pregnancy and the risk of congenital heart defects. Medicina (Kaunas) 45: pp. 904-909
  20. Williams, LJ, Correa, A, Rasmussen, S (2004) Maternal lifestyle factors and risk for ventricular septal defects. Birth Defects Res A Clin Mol Teratol 70: pp. 59-64 CrossRef
  21. Ewing, CK, Loffredo, CA, Beaty, TH (1997) Paternal risk factors for isolated membranous ventricular septal defects. Am J Med Genet 71: pp. 42-46 CrossRef
  22. Steinberger, EK, Ferencz, C, Loffredo, CA (2002) Infants with single ventricle: a population-based epidemiological study. Teratology 65: pp. 106-115 CrossRef
  23. Browne, ML (2006) Maternal exposure to caffeine and risk of congenital anomalies: a systematic review. Epidemiology 17: pp. 324-331 CrossRef
  24. Fixler, DE, Threlkeld, N (1998) Prenatal exposures and congenital heart defects in Down syndrome infants. Teratology 58: pp. 6-12 CrossRef
  25. Torfs, CP, Christianson, RE (1999) Maternal risk factors and major associated defects in infants with Down syndrome. Epidemiology 10: pp. 264-270 CrossRef
  26. Stothard, KJ, Tennant, PW, Bell, R, Rankin, J (2009) Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis. JAMA 301: pp. 636-650 CrossRef
  27. Cai, GJ, Sun, XX, Zhang, L, Hong, Q (2014) Association between maternal body mass index and congenital heart defects in offspring: a systematic review. Am J Obstet Gynecol 211: pp. 91-117 CrossRef
  28. Block, SR, Watkins, SM, Salemi, JL, Rutkowski, R, Tanner, JP, Correia, JA, Kirby, RS (2013) Maternal pre-pregnancy body mass index and risk of selected birth defects: evidence of a dose鈥搑esponse relationship. Paediatr Perinat Epidemiol 27: pp. 521-531 CrossRef
  29. Zhu, JL, Olsen, J, Sorensen, HT, Li, J, Nohr, EA, Obel, C, Vestergaard, M, Olsen, MS (2013) Prenatal maternal bereavement and congenital heart defects in offspring: a registry-based study. Pediatrics 131: pp. e1225-e1230 CrossRef
  30. Liu, S, Liu, J, Tang, J, Ji, J, Chen, J, Liu, C (2009) Environmental risk factors for congenital heart disease in the Shandong Peninsula, China: a hospital-based case鈥揷ontrol study. J Epidemiol 19: pp. 122-130 CrossRef
  31. Alberman, ED, Goldstein, H (1971) Possible teratogenic effect of cigarette smoking. Nature 231: pp. 529-530 CrossRef
  32. Chehab, G, El-Rassi, I, Adhami, A, Chokor, I, Chatila, F, Haddad, W, Saliba, Z (2012) Parental smoking during early pregnancy and congenital heart defects. J Med Liban 60: pp. 14-18
  33. Clarren, SK, Smith, DW (1978) The fetal alcohol syndrome. N Engl J Med 298: pp. 1063-1067 CrossRef
  34. Nehlig, A, Debry, G (1994) Potential teratogenic and neurodevelopmental consequences of coffee and caffeine exposure: a review on human and animal data. Neurotoxicol Teratol 16: pp. 531-543 CrossRef
  35. Flegal, KM, Carroll, MD, Ogden, CL, Curtin, LR (2010) Prevalence and trends in obesity among US adults, 1999鈥?008. JAMA 303: pp. 235-241 CrossRef
  36. Athukorala, C, Rumbold, AR, Willson, KJ, Crowther, CA (2010) The risk of adverse pregnancy outcomes in women who are overweight or obese. BMC Pregnancy Childbirth 10: pp. 56 CrossRef
  37. Sebire, NJ, Jolly, M, Harris, JP, Wadsworth, J, Joffe, M, Beard, RW, Regan, L, Robinson, S (2001) Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. Int J Obes Relat Metab Disord 25: pp. 1175-1182 CrossRef
  38. Abenhaim, HA, Kinch, RA, Morin, L, Benjamin, A, Usher, R (2007) Effect of prepregnancy body mass index categories on obstetrical and neonatal outcomes. Arch Gynecol Obstet 275: pp. 39-43 CrossRef
  39. Weiss, JL, Malone, FD, Emig, D, Ball, RH, Nyberg, DA, Comstock, CH, Saade, G, Eddleman, K, Carter, SM, Craigo, SD, Carr, SR, D'Alton, ME (2004) Obesity, obstetric complications and cesarean delivery rate鈥揳 population-based screening study. Am J Obstet Gynecol 190: pp. 1091-1097 CrossRef
  40. Alverson, CJ, Strickland, MJ, Gilboa, SM, Correa, A (2011) Maternal smoking and congenital heart defects in the Baltimore-Washington Infant Study. Pediatrics 127: pp. e647-e653 CrossRef
  41. Rooij, IA, Wegerif, MJ, Roelofs, HM, Peters, WH, Kuijpers-Jagtman, AM, Zielhuis, GA, Merkus, HM, Steegers-Theunissen, RP (2001) Smoking, genetic polymorphisms in biotransformation enzymes, and nonsyndromic oral clefting: a gene-environment interaction. Epidemiology 12: pp. 502-507 CrossRef
  42. Lupo, PJ, Langlois, PH, Reefhuis, J, Lawson, CC, Symanski, E, Desrosiers, TA, Khodr, ZG, Agopian, AJ, Waters, MA, Duwe, KN, Finnell, RH, Mitchell, LE, Moore, CA, Romitti, PA, Shaw, GM (2012) Maternal occupational exposure to polycyclic aromatic hydrocarbons: effects on gastroschisis among offspring in the National Birth Defects Prevention Study. Environ Health Perspect 120: pp. 910-915 CrossRef
  43. Barbieri, O, Ognio, E, Rossi, O, Astigiano, S, Rossi, L (1986) Embryotoxicity of benzo(a)pyrene and some of its synthetic derivatives in Swiss mice. Cancer Res 46: pp. 94-98
  44. Binkhorst, M, Wortmann, SB, Funke, S, Kozicz, T, Wevers, RA, Morava, E (2012) Glycosylation defects underlying fetal alcohol spectrum disorder: a novel pathogenetic model. 鈥淲hen the wine goes in, strange things come out鈥?- S.T. Coleridge, The Piccolomini. J Inherit Metab Dis 35: pp. 399-405 CrossRef
  45. Flentke, GR, Garic, A, Amberger, E, Hernandez, M, Smith, SM (2011) Calcium-mediated repression of beta-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome. Birth Defects Res A Clin Mol Teratol 91: pp. 591-602 CrossRef
  46. Marrs, JA, Clendenon, SG, Ratcliffe, DR, Fielding, SM, Liu, Q, Bosron, WF (2010) Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement. Alcohol 44: pp. 707-715 CrossRef
  47. Serrano, M, Han, M, Brinez, P, Linask, KK (2010) Fetal alcohol syndrome: cardiac birth defects in mice and prevention with folate. Am J Obstet Gynecol 203: pp. 75 CrossRef
  48. Menegola, E, Broccia, ML, Renzo, F, Giavini, E (2001) Acetaldehyde in vitro exposure and apoptosis: a possible mechanism of teratogenesis. Alcohol 23: pp. 35-39 CrossRef
  49. Ranheim, T, Halvorsen, B (2005) Coffee consumption and human health鈥揵eneficial or detrimental?鈥揗echanisms for effects of coffee consumption on different risk factors for cardiovascular disease and type 2 diabetes mellitus. Mol Nutr Food Res 49: pp. 274-284 CrossRef
  50. Hobbs, CA, Cleves, MA, Melnyk, S, Zhao, W, James, SJ (2005) Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism. Am J Clin Nutr 81: pp. 147-153
  51. Allen, MI (1981) Fetal vascular disruptions: mechanisms and some resulting birth defects. Pediatr Ann 10: pp. 219-233
  52. Loeken, MR (2004) Free radicals and birth defects. J Matern Fetal Neonatal Med 15: pp. 6-14 CrossRef
  53. Nielsen, GL, Norgard, B, Puho, E, Rothman, KJ, Sorensen, HT, Czeizel, AE (2005) Risk of specific congenital abnormalities in offspring of women with diabetes. Diabet Med 22: pp. 693-696 CrossRef
  
• 刊物主题：Pediatrics; Maternal and Child Health;
• 出版者：BioMed Central
• ISSN：1824-7288

文摘

The prognosis of children with congenital heart defects(CHDs) continues to improve with advancing surgical techniques; however, lack of information about modifiable risk factors for malformations in cardiovascular development impeded the prevention of CHDs. We investigated an association between maternal lifestyle factors and the risk of CHDs, because epidemiological studies have reported conflicting results regarding maternal lifestyle factors and the risk of CHDs recently. A review published on 2007 provided a summary of maternal exposures associated with an increased risk of CHDs. As part of noninherited risk factors, we conducted a brief overview of studies on the evidence linking common maternal lifestyle factors, specifically smoking, alcohol, illicit drugs, caffeine, body mass index and psychological factors to the development of CHDs in offspring. Women who smoke and have an excessive body mass index(BMI) during pregnancy are suspected to be associated with CHDs in offspring. Our findings could cause public health policy makers to pay more attention to women at risk and could be used in the development of population-based prevention strategies to reduce the incidence and burden of CHDs. However, more prospective studies are needed to investigate the association between maternal lifestyle factors and CHDs.