Perioperative Status and Complications in Opium Addicts in Western Rajasthan
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  • 作者:Ajay Malviya (1)
    Nitin Negi (2) (3)
    Manish Mandora (1)
    J. K. Yadav (1)
  • 关键词:Opium addiction ; Social custom ; Opium initiation ceremony ; Opiate withdrawal syndrome ; Sphincter of oddi dysfunction (SOD)
  • 刊名:Indian Journal of Surgery
  • 出版年:2011
  • 出版时间:October 2011
  • 年:2011
  • 卷:73
  • 期:5
  • 页码:346-351
  • 全文大小:102KB
  • 参考文献:1. Jaffe JH, Martin WR (1990) Opioid analgesics and antagonists. In: Gilman AG, Goodman LS (eds) The pharmacological basis of therapeutics, 8th edn. Riverside, New Jersey, pp 485-21
    2. Paoli L, Greenfield VA, Charles M, Reuter P (2009) The global diversion of pharmaceutical drugs. India: the third largest illicit opium producer? Addiction 104(3):347-54 CrossRef
    3. Purohit DR, Vyas BR, Limba PR (1982) Opium de-addiction camp II. J Clin Psychiatry India 6:98-06
    4. Purohit DR (1988) Community approach to opium dependent subjects in rural area of Rajasthan. J Community Psychiatr 11:3-
    5. Ganguly KK, Sharma HK, Krishnamachari KA (1995) An ethnographic account of opium consumers of Rajasthan (India): socio-medical perspective. Addiction 90(1):9-2 CrossRef
    6. Mathur ML, Bansal RK, Dixit AK (1991) Prevalence of opium consumption in rural population of a desert district, Jodhpur. Indian J Public Health 35(4):117-18
    7. Chang KJ, Cooper BR, Hazum E et al (1979) Multiple opiate receptors: different regional distribution in brain and differential binding of opiates and opioid peptides. Mol Pharmacol 16:91-04
    8. Helm JF, Venu RP, Geenen JE et al (1998) Effects of morphine on the human sphincter of Oddi. Gut 29:1402-407 CrossRef
    9. Sharma SS (2002) Sphincter of Oddi dysfunction in patients addicted to opium: an unrecognized entity. Gastrointest Endosc 55(3):427-30 CrossRef
    10. Yap CK, Chong R, Ng HS (1995) Dilated common bile duct in opium addicts: old disease, new observations for the biliary endoscopist. J Gastro Hepatol 10(suppl 3): A96, K127.
    11. Chuah SY, Leong CK, Pang CW (2003) Dilated common bile duct in opium addicts with and without biliary symptoms—implication for research in AIDS cholangiopathy. Singapore Med J 44:261-67
    12. Farahmand H, PourGholami M, Fathollah MS (2007) Chronic extrahepatic bile duct dilatation: sonographic screening in patients with opioid addiction. Korean J Radiol 8(3):212-15 kjr.2007.8.3.212">CrossRef
    13. Friedman R, Kamel I, Perez C et al (2003) Severe intraoperative hypertension and opioid–resistant postoperative pain in a methadone-treated patient. J Pain 4(5):289-90 CrossRef
    14. Macutkiewicz C, Anwar S, Babbas C et al (2004) Opiate withdrawal syndrome mimicking postoperative intestinal obstruction. Ann R Coll Surg Engl 86(2):96-8 CrossRef
    15. Asgary S, Sarrafzadegan N, Naderi GA, Rozbehani R (2008) Effect of opium addiction on new and traditional cardiovascular risk factors: do duration of addiction and route of administration matter? Lipids Health Dis 7:42 CrossRef
    16. Gorgaslidze AG, Sa?fullaeva MA, Kuz’mina MM, Golitsina LS, Smetnev AS (1993) Cardiac arrhythmia and myocardial contraction in opium and ephedrone addiction. Kardiologiia 33(1):14-6
    17. Mathur ML, Chaudhary RC (1996) Increased risk of tuberculosis in opium addicts. Indian J Med Sci 50(10):365-67
    18. Vas L (1997) Unusual problem with pain relief in an opium addict. Pain 69(1-):203-04 CrossRef
    19. Clark NC, Lintzeris N, Muhleisen PJ (2002) Severe opiate withdrawal in a heroin user precipitated by a massive buprenorphine dose. MJA 176(4):166-67
    20. Wesson DR, Ling W (2003) The Clinical opiate withdrawal scale (COWS). J Psychoactive Drugs 35(2):253-59 CrossRef
  • 作者单位:Ajay Malviya (1)
    Nitin Negi (2) (3)
    Manish Mandora (1)
    J. K. Yadav (1)

    1. Department of Surgery, Dr. S.N. Medical College, Jodhpur, Rajasthan, India
    2. Dr. S.N. Medical College, Jodhpur, Rajasthan, India
    3. Department of Surgery, Dr. S.N. Medical College, F-706, Behind Jawahar Kala Kendra, Gandhi Nagar, Jaipur, Pin-302015, India
文摘
Opium addiction is rampant in Western Rajasthan and probably has the highest number of opium addicts in the world. The study envisages upon the presentation, diagnosis and various postoperative complications in surgically ill opium addicts vis-à-vis non addicts. The study is purported to benefit clinicians dealing with opium addict patients. The prospective cohort study was conducted at Mahatma Gandhi Hospital, Jodhpur between December 2004 and February 2006 and included cohorts of 71 opium addict and 50 non-addict patients admitted in various surgical wards. The study focused on presentation and the post-surgical complications encountered in these patients vis-à-vis others. The results thus obtained were evaluated statistically (mean±SD, SEM, two tailed t test, chi-square test), p value of <0.05 was considered as significant. A thorough comparative analysis revealed that opium addict patients had a significantly higher incidence of postoperative respiratory, cardiovascular, systemic and local complications. The requirement of analgesics and duration of hospital stay were also significantly higher as compared to control group. The work concludes that opium addicts suffer a much higher degree of postoperative morbidity as compared to non-addicts.

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