Development of a Nile-Blue Based Chemodosimeter for Hg2+ in Aqueous Solution and its Application in Biological Imaging
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- 作者：Mingming Hu ; Jianhua Yin ; Yahong Li ; Xiaofang Zhao
- 关键词：Chemodosimeter ; Fluorescent probe ; Hg2+ detection ; Nile ; blue
- 刊名：Journal of Fluorescence
- 出版年：2015
- 出版时间：March 2015
- 年：2015
- 卷：25
- 期：2
- 页码：403-408
- 全文大小：724 KB
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文摘
A Nile blue-based chemodosimeter was newly synthesized. It can detect Hg2+ in aqueous solution based on desulfurization reaction. Upon its addition into aqueous Hg2+ ion solution, it exhibited a considerable blue-shift in its absorption and obvious fluorescence quenching. The detection mechanism was proved by mass spectrometry analysis and Gaussian calculations. Detection at an emission of 685?nm was extremely sensitive, with a detection limit of 2.5?×-0??mol/L. The fluorescent images in living cells and zebrafish demonstrate its potential for studying the accumulation of mercury species in organism.