Blending PLLA/tannin-grafted PCL fiber membrane for skin tissue engineering
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- 作者：Suchen Jiang ; Ping Song ; Huiling Guo ; Xue Zhang ; Yajun Ren…
- 刊名：Journal of Materials Science
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：52
- 期：3
- 页码：1617-1624
- 全文大小：
- 刊物类别：Chemistry and Materials Science
- 刊物主题：Materials Science, general; Characterization and Evaluation of Materials; Polymer Sciences; Continuum Mechanics and Mechanics of Materials; Crystallography and Scattering Methods; Classical Mechanics;
- 出版者：Springer US
- ISSN：1573-4803
- 卷排序：52
文摘
To create novel materials of skin tissue engineering, the blends of tannin-grafted poly(ɛ-caprolactone) (TA-g-PCL) and poly(l-lactic acid) (PLLA) have been prepared by electrospinning, and their corresponding characteristics are evaluated such as morphology, FTIR, thermodynamics, mechanics, wettability, as well as biocompatibility. TA-g-PCL and PLLA can be well blended to make smooth fibers, and fibrous diameter turns thinner with blending TA-g-PCL. At 15 wt%, the fibrous membrane shows higher tensile strength and elongation at a break than the other samples due to its best crystallinity. Membranous wettability drops with blending TA-g-PCL, but it increases sharply after incorporating PF108. At the same time, PLLA/TA-g-PCL fiber membrane is biocompatible. The biodegradable PLLA/TA-g-PLLA membrane is a promising candidate as skin tissue engineering.