Efficacy of percutaneous ethanol sclerotherapy for venous malformation in lower extremities: a retrospective review of 21 cases

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• 作者：Hiroshi Furukawa (1)
  Satoru Sasaki (2)
  Akihiko Oyama (1)
  Emi Funayama (1)
  Toshihiko Hayashi (1)
  Noriko Saito (2)
  Munetomo Nagao (3)
  William Mol (1)
  Yuhei Yamamoto (1)
  
• 关键词：Venous malformation (VM) ; Intramuscular ; Lower extremities ; Ethanol sclerotherapy ; Postinterventional VM score
• 刊名：European Journal of Plastic Surgery
• 出版年：2013
• 出版时间：February 2013
• 年：2013
• 卷：36
• 期：2
• 页码：105-110
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• 作者单位：Hiroshi Furukawa (1)
  Satoru Sasaki (2)
  Akihiko Oyama (1)
  Emi Funayama (1)
  Toshihiko Hayashi (1)
  Noriko Saito (2)
  Munetomo Nagao (3)
  William Mol (1)
  Yuhei Yamamoto (1)
  
  1. Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Hokkaido at Sapporo (UHS), Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan
  2. The Center for Hemangioma/Vascular Malformation, Tonan Hospital, KKR Sapporo Medical Center, Sapporo, Japan
  3. Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Iwate Medical University, Morioka, Japan
  
• ISSN：1435-0130

文摘

Background Venous malformations (VM) of lower extremities have characteristic symptoms, especially swelling, pain at rest or with dependence, or in the morning, or with exertion. Sclerotherapy has been applied and has been showed to alleviate the associated signs and symptoms. The aim of this study is to evaluate the outcomes of ethanol sclerotherapy for VM of lower extremities. Methods The 21 patients of intramuscular VM of the lower extremities, who received percutaneous sclerotherapy using absolute ethanol in our institute, were reviewed retrospectively. The average age at the time of the initial diagnosis was 18.6?years, and average follow-up period after last sclerotherapy is 19.4?±-3.5?months. The postinterventional changes of the associated signs and symptoms were evaluated by utilizing original VM scoring system. Results The average number of sclerotherapy sessions was 2.6 times per case. The average total amount of ethanol used in each patient was 41.3?ml. Sclerotherapy reduced the associated signs and symptoms in many of the patients (n--9/21). Preinterventional VM score as the overall baseline status was 10, and the average VM score after sclerotherapy was 4.1. There was no inverse correlation between the amount of ethanol used and the VM score. In seven cases treated more than three times, reverse correlation between the “VM score-and the number of sclerotherapy sessions was demonstrated (p-lt;-.05, ρ--.8214). Conclusions The characteristic symptoms and signs of the VM were improved by sclerotherapy. More than three sessions of ethanol sclerotherapy improved the overall status of extensive intramuscular VM in lower extremities. Level of Evidence: Level IV, therapeutic study.