The polymorphisms of LYRM1 gene and their association with body measurement and ultrasound traits of Qinchuan cattle

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• 作者：Yaokun Li (1)
  Jianbin Gao (1)
  Ning Yang (1)
  Changzhen Fu (1)
  Gong Cheng (1) (2)
  Hongbao Wang (1) (2)
  Linsen Zan (1) (2)
  
• 关键词：Body measurement and meat quality traits ; Qinchuan cattle ; LYRM1 ; SNPs
• 刊名：Molecular Biology Reports
• 出版年：2013
• 出版时间：February 2013
• 年：2013
• 卷：40
• 期：2
• 页码：1511-1517
• 全文大小：380KB
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• 作者单位：Yaokun Li (1)
  Jianbin Gao (1)
  Ning Yang (1)
  Changzhen Fu (1)
  Gong Cheng (1) (2)
  Hongbao Wang (1) (2)
  Linsen Zan (1) (2)
  
  1. College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, Shaanxi, People’s Republic of China
  2. National Beef Cattle Improvement Center of Northwest A & F University, Yangling, 712100, Shaanxi, People’s Republic of China
  
• ISSN：1573-4978

文摘

Body measurement and meat quality traits which play important roles in the assessment of productivity and economy in cattle were influenced by genes and environmental factors. Latest studies showed that LYR motif containing 1 (LYRM1) may be involved in influencing fatness deposition in animals. The objective of this study was to detect bovine LYRM1 gene polymorphism and analyze its association with body measurement and meat quality traits of cattle. Blood samples were taken from a total of 404 Qinchuan cattle aged from 18-4?months. Created restriction site-polymerase chain reaction-restriction fragment length polymorphism (CRS-PCR–RFLP) and DNA sequencing were used to find out LYRM1 single polymorphism nucleotide (SNPs). Sequence analysis of LYRM1 gene revealed two SNPs (g.165 C?>?A, g.193 A?>?G) in 3-untranslated region (3′UTR) of exon 3. And g.165 C?>?A showed two genotypes namely AC and CC while g.193 A?>?G showed three genotypes: AA, AG and GG. Analysis results showed that there were significant associations between polymorphism of these two and body measurement and meat quality traits in Qinchuan cattle population. Based on the results obtained from this study, it is inferred that LYRM1 gene may have potential effects on body measurement and meat quality traits in Qinchuan cattle population and could be used for marker-assisted selection.