Idiopathic severe constriction of the fetal ductus arteriosus: a possible underestimated pathophysiology
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  • 作者:Yoshio Shima (1) (3)
    Hiroko Ishikawa (1)
    Yoshikatsu Matsumura (2)
    Kentaro Yashiro (2)
    Mizue Nakajima (2)
    Makoto Migita (1)
  • 关键词:Ductus arteriosus ; Prenatal diagnosis
  • 刊名:European Journal of Pediatrics
  • 出版年:2011
  • 出版时间:February 2011
  • 年:2011
  • 卷:170
  • 期:2
  • 页码:237-240
  • 全文大小:166KB
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  • 作者单位:Yoshio Shima (1) (3)
    Hiroko Ishikawa (1)
    Yoshikatsu Matsumura (2)
    Kentaro Yashiro (2)
    Mizue Nakajima (2)
    Makoto Migita (1)

    1. Department of Pediatrics, Nippon Medical School, Tokyo, Japan
    3. Department of Pediatrics, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12, Tateishi, Katsushika-ku, Tokyo, 124-0012, Japan
    2. Department of Pediatrics, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, Japan
文摘
Idiopathic intrauterine constriction/closure of the ductus arteriosus, which is distinct from that secondary to maternal exposure to non-steroidal anti-inflammatory drugs, such as indomethacin, or structural cardiac defect, is an uncommon event that often results in severe fetal–neonatal morbidity and mortality. We reported a case of idiopathic fetal ductal constriction, in which the diagnosis was confirmed by documentation of an abnormal four-chamber view of the fetal heart at 38?weeks of gestation on obstetric ultrasound examination. A female infant weighing 2,816?g was born by Cesarean section, and her postnatal course was mild; transient tachypnea requiring only several days of supplemental oxygen with spontaneous regression of the abnormal echocardiographic findings by 3?months of age. The incidence of idiopathic constriction/closure of the fetal ductus arteriosus may be underestimated, particularly with a negative history of maternal drug exposure and mild postnatal clinical presentation.

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