A case of a fibroadenoma coexisting with an invasive lobular carcinoma in the breast

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• 作者：Shinya Tajima (1)
  Yoshihide Kanemaki (1)
  Yasuyuki Kurihara (1)
  Kyoko Okamoto (1)
  Hiroshi Shimamoto (1)
  Hiroko Okazaki (1)
  Itsuko Okuda (4)
  Futoshi Kawahara (2)
  Yasuo Nakajima (1)
  Mamoru Fukuda (2)
  Ichiro Maeda (3)
  
• 关键词：Fibroadenoma ; Invasive lobular carcinoma ; High ; resolution magnetic resonance imaging (HR ; MRI) ; Breast ; Calcification
• 刊名：Breast Cancer
• 出版年：2011
• 出版时间：October 2011
• 年：2011
• 卷：18
• 期：4
• 页码：319-323
• 全文大小：2078KB
• 参考文献：1. Bellocq JP, Magro G. Fibroepithelial tumors. In: Tavassoli FA, Devilee P, editors. World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of the Breast and Female Genital Organs. Lyon: IARC Press; 2003. p. 99鈥?03.
  2. Ellis IO, Cornelisse CJ, Schnitt SJ, Sasco AJ, Sastre-Garau X, Kaaks R, et al. Invasive breast carcinoma. In: Tavassoli FA, Devilee P, editors. World Health Organization Classification of Tumors. Pathology and genetics of tumors of the breast and female genital organs. Lyon: IARC Press; 2003. p. 23鈥?7.
  3. Abe H, Hanasawa K, Naitoh H, Endo Y, Tani T, Kushima R, et al. Invasive ductal carcinoma within a fibroadenoma of the breast. Int J Clin Oncol. 2004;9(4):334鈥?. CrossRef
  4. Kurosumi M, Itokazu R, Mamiya Y, Kishi K, Takayama S, Nagasawa M, et al. Invasive ductal carcinoma with a predominant intraductal component arising in a fibroadenoma of the breast. Pathol Int. 1994;44:874鈥?. CrossRef
  5. Arima M, Kusama M, Murata A, Fujii M, Suzuki Y, Furuta M, et al. Noninvasive ductal carcinoma within a fibroadenoma treated with breast-conserving surgery. Jpn J Breast Cancer. 1996;11(2):340鈥?.
  6. Rosen PP, editors. Unusual clinical presentations of carcinoma. In: Rosen鈥檚 breast pathology. 2nd ed. Philadelphia: Williams & Wilkins; 2001. p. 656鈥?61.
  7. Borecky N, Rickard M. Preoperative diagnosis of carcinoma within fibroadenoma on screening mammograms. J Med Imaging Radiat Oncol. 2008;52(1):64鈥?. CrossRef
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  9. Matsubayashi R, Matsuo Y, Edakuni G, Satoh T, Tokunaga O, Kudo S. Breast masses with peripheral rim enhancement on dynamic contrast enhanced MR images: correlation of MR findings with histologic features and expression of growth factors. Radiology. 2000;217:841鈥?.
  10. Yoshihide K, Yasuyuki K, Kyoko O, Yasuo N, Mamoru F, Ichiro M, et al. Ductal carcinoma in situ: correlations between high-resolution magnetic resonance imaging and histopathology. Radiat Med. 2007;25:1鈥?. CrossRef
  11. Rosen PP, editors. Fibroepithelial neoplasms. In: Rosen鈥檚 breast pathology. 2nd ed. Philadelphia: Williams & Wilkins; 2001. p. 163鈥?76.
  12. Rosen PP, editors. Invasive lobular carcinoma. In: Rosen鈥檚 breast pathology. 2nd ed. Philadelphia: Williams & Wilkins; 2001. p. 627鈥?52.
  
• 作者单位：Shinya Tajima (1)
  Yoshihide Kanemaki (1)
  Yasuyuki Kurihara (1)
  Kyoko Okamoto (1)
  Hiroshi Shimamoto (1)
  Hiroko Okazaki (1)
  Itsuko Okuda (4)
  Futoshi Kawahara (2)
  Yasuo Nakajima (1)
  Mamoru Fukuda (2)
  Ichiro Maeda (3)
  
  1. Department of Radiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan
  4. Department of Diagnostic Radiology, Toranomon Hospital, Tokyo, Japan
  2. Department of Breast Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan
  3. Department of Pathology, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan
  

文摘

A case of a fibroadenoma coexisting with an invasive lobular carcinoma of the breast in a 60-year-old female is presented, and its pathological features are correlated with high-resolution magnetic resonance imaging (HR-MRI) and other imaging findings. The patient presented with the chief complaint of having a palpable mass in her right breast for 3 months. Mammography revealed a lobular mass with a micro-lobulated margin, which suggested a malignant nature; however, it included coarse calcifications. Sonographic imaging and HR-MRI findings were compatible with malignant tumor. Cytology was performed, and the results indicated an invasive carcinoma. Breast-conserving surgery was performed as a curative operation. The pathological features revealed a fibroadenoma coexisting with an invasive lobular carcinoma. This case suggests that radiologists should always pay attention to the associated malignant imaging characteristics, such as the shape and border of the mass, whenever a mass demonstrates benign-like calcifications.