Detecting Primary KIT Mutations in Presurgical Plasma of Patients with Gastrointestinal Stromal Tumor

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• 作者：Guhyun Kang ; Byeong Seok Sohn ; Jung-Soo Pyo ; Jung Yeon Kim…
• 刊名：Molecular Diagnosis & Therapy
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：20
• 期：4
• 页码：347-351
• 全文大小：403 KB
• 刊物主题：Molecular Medicine; Human Genetics; Cancer Research; Laboratory Medicine; Pharmacotherapy;
• 出版者：Springer International Publishing
• ISSN：1179-2000
• 卷排序：20

文摘

IntroductionAssessment of KIT/PDGFRA mutations is essential for therapeutic decision making in patients with gastrointestinal stromal tumor (GIST). Blood-derived circulating tumor DNA can provide molecular information representative of the tumor tissue.