Anti-atherogenic properties of emulsified perilla oil (EPO) in apo E KO mice and plasma lipid lowering effects of rice porridge containing EPO in healthy young adults
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- 作者：Hyejin Jo (1)
Mijeong Kim (1)
Jihyun Lee (2)
Hunjung Kim (2)
Yeong Ok Song (1) - 关键词：perilla porridge ; apo E KO mice ; young adult ; plasma lipid ; fatty streak lesion size
- 刊名：Food Science and Biotechnology
- 出版年：2013
- 出版时间：February 2013
- 年：2013
- 卷：22
- 期：1
- 页码：79-85
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Mijeong Kim (1)
Jihyun Lee (2)
Hunjung Kim (2)
Yeong Ok Song (1)
1. Department of Food Science and Nutrition & Kimchi Research Institute, Pusan National University, Busan, 609-735, Korea
2. Nongshim R&D Center, Seongnam, Gyeonggi, 463-746, Korea - ISSN：2092-6456
文摘
The objective of this study was to develop a rice porridge containing perilla oil rich in 伪-linolenic acid which demonstrated anti-atherogenic effect in the previous study. Lipid lowering effect of emulsified perilla oil (EPO) was examined in apo E KO mice (n=18) and that for rice porridge containing EPO (RPEPO) was investigated in the pilot scale human study (n=20). Inhibitory effects of EPO on the plasma lipid levels and fatty streak lesion size in apo E KO mice were similar to those observed in mice fed perilla oil (PO), suggesting that EPO is applicable form of PO in manufacturing rice porridge product with PO鈥檚 health benefit properties. In human study with young adults aged between 20鈥?5 years old, changes in plasma triglyceride concentration of subjects consumed RPEPO for 30 days as a breakfast was significantly lowered than those for subjects consumed rice porridge (p<0.05), of which calorie levels were the same (333 kcal/meal).