Effects of packed red blood cell storage duration on post-transfusion clinical outcomes: a meta-analysis and systematic review
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  • 作者:Monica Suet Ying Ng ; Angela Suet Yeung Ng ; Jessica Chan…
  • 关键词:Meta ; analysis ; Systematic review ; Red blood cells ; Transfusion ; Blood storage ; Erythrocyte transfusion
  • 刊名:Intensive Care Medicine
  • 出版年:2015
  • 出版时间:December 2015
  • 年:2015
  • 卷:41
  • 期:12
  • 页码:2087-2097
  • 全文大小:831 KB
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  • 作者单位:Monica Suet Ying Ng (1) (2) (3)
    Angela Suet Yeung Ng (1) (2)
    Jessica Chan (2)
    John-Paul Tung (1) (2) (3)
    John Francis Fraser (1) (2)

    1. Critical Care Research Group, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD, Australia
    2. School of Medicine, The University of Queensland, Herston, Brisbane, QLD, Australia
    3. Research and Development, Australian Red Cross Blood Service, Kelvin Grove, Brisbane, QLD, Australia
  • 刊物主题:Intensive / Critical Care Medicine; Anesthesiology; Emergency Medicine; Pneumology/Respiratory System; Pain Medicine; Pediatrics;
  • 出版者:Springer Berlin Heidelberg
  • ISSN:1432-1238
文摘
Purpose There is substantial conjecture regarding the clinical significance of packed red blood cell (PRBC) changes that occur during in vitro storage. Here, we present a meta- and systematic analysis of adult studies published between 1994 and 2015 with the aim of updating existing quantitative reviews and providing a comprehensive cover of the six most commonly studied outcomes—mortality, infection, renal dysfunction, multiple organ dysfunction syndrome (MODS), thrombotic complications and prolonged hospital length of stay.

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