MicroRNAs are potential prognostic and therapeutic targets in diabetic osteoarthritis

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• 作者：Shi Jingsheng ; Wei Yibing ; Xia Jun ; Wang Siqun…
• 关键词：MicroRNA ; Type II diabetes ; Osteoarthritis chondrocyte
• 刊名：Journal of Bone and Mineral Metabolism
• 出版年：2015
• 出版时间：January 2015
• 年：2015
• 卷：33
• 期：1
• 页码：1-8
• 全文大小：569 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Metabolic Diseases
  Orthopedics
  Internal Medicine
  
• 出版者：Springer Japan
• ISSN：1435-5604

文摘

Osteoarthritis is an aging-related degenerative disease that severely influences the elders-life quality. However, there have been few clinical approaches available until now. Currently, more knowledge of the pathology of osteoarthritis has been illustrated. Especially, diabetes can be the only predictor of osteoarthritis. Due to its outstanding characteristics, MicroRNA has been considered as an efficient target in treating diseases. In this review, we will discuss a new insight focusing on the roles of microRNA in the progression of osteoarthritis-induced by diabetes, especially type II diabetes mellitus.