Thyroid Adenoma with Extensive Extracellular Mucin Deposition: Report of a Case

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• 作者：Saburo Murakami ; Hideto Sakata ; Katsuhiko Okubo ; Yoshitaka Tsuji and Hidekazu Kayano
• 关键词：Thyroid adenoma ; Myxoid stroma ; Alcian blue
• 刊名：Surgery Today
• 出版年：2007
• 出版时间：March, 2007
• 年：2007
• 卷：37
• 期：3
• 页码：226-229
• 全文大小：180 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Surgery
  Abdominal Surgery
  Thoracic Surgery
  Vascular Surgery
  Cardiac Surgery
  Surgical Oncology
  
• 出版者：Springer Japan
• ISSN：1436-2813

文摘

A thyroid tumor with extensive extracellular mucin deposition is extremely rare. We herein describe a case of a thyroid adenoma with prominent myxoid stroma. A 63-year-old man presented with a mass in his right anterior neck. Radiological examinations showed this mass to be a thyroid tumor with a cystic component. The histopathological findings showed the stroma of this tumor to consist of abundant myxoid materials which stained gray-bluish for hematoxylin-eosin. The myxoid material was positive for alcian blue, whereas periodic acid-Schiff did not stain this material. No intracytoplasmic mucin was identified. In an immunohistochemical study, the tumor cells were negative for cytokeratin 19. Furthermore, positive staining was observed for thyroglobulin while a negative finding was seen for calcitonin.