Effect of high-dose cholecalciferol (vitamin D₃) on bone and body composition in children and young adults with HIV infection: a randomized, double-blind, placebo-controlled trial

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• 作者：A. J. Rovner ; V. A. Stallings ; R. Rutstein ; J. I. Schall&#8230
• 关键词：Cholecalciferol ; Dual energy X ; ray absorptiometry ; HIV ; Peripheral quantitative computed tomography
• 刊名：Osteoporosis International
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：1
• 页码：201-209
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Orthopedics; Endocrinology; Rheumatology;
• 出版者：Springer London
• ISSN：1433-2965
• 卷排序：28

文摘

SummaryIt is unknown whether vitamin D supplementation positively impacts body composition and bone outcomes in children and young adults with HIV. This RCT found that despite increasing 25(OH)D concentrations, high dose vitamin D₃ supplementation did not impact bone or body composition in children and young adults with HIV infection.