The modifying effect of vitamin C on the association between perfluorinated compounds and insulin resistance in the Korean elderly: a double-blind, randomized, placebo-controlled crossover trial
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作者单位:Jin Hee Kim (1) Hye Yin Park (2) Jung Dae Jeon (3) Younglim Kho (3) Seung-Kyu Kim (4) Min-Seon Park (5) Yun-Chul Hong (2) (6)
1. Department of Environmental Health, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea 2. Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 110-799, Republic of Korea 3. Department of Health, Environment and Safety, Eulji University, Sungnam, Republic of Korea 4. Department of Marine Science, College of Natural Sciences, University of Incheon, Incheon, Republic of Korea 5. Department of Family Medicine, Seoul National University Hospital, Seoul, Republic of Korea 6. Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea
刊物类别:Chemistry and Materials Science
刊物主题:Chemistry Nutrition
出版者:Springer Berlin / Heidelberg
ISSN:1436-6215
文摘
Purpose There is limited evidence whether environmental exposure to perfluorinated compounds (PFCs) affects insulin resistance (IR) and whether vitamin C intake protects against the adverse effect of PFCs. This study was carried out to investigate the effect of PFCs on IR through oxidative stress, and the effects of a 4-week consumption of vitamin C supplement compared placebo on development of IR by PFCs.