Rapid Identification and Quantification of Linear Olefin Isomers by Online Ozonolysis-Single Photon Ionization Time-of-Flight Mass Spectrometry

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• 作者：Yuanyuan Xie ; Ping Chen ; Lei Hua ; Keyong Hou…
• 关键词：Olefin ; Double bond position ; Time ; of ; flight mass spectrometry ; Ozonolysis
• 刊名：Journal of The American Society for Mass Spectrometry
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：27
• 期：1
• 页码：144-152
• 全文大小：2,006 KB
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• 作者单位：Yuanyuan Xie (1) (2)
  Ping Chen (1)
  Lei Hua (1)
  Keyong Hou (1)
  Yongchao Wang (1)
  Haiyan Wang (3)
  Haiyang Li (1)
  
  1. Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, People’s Republic of China
  2. Graduate University of Chinese Academy of Sciences, Beijing, 100049, People’s Republic of China
  3. Jiangsu Province Institute of Quality and Safety Engineering, Nanjing, Jiangsu, 210046, People’s Republic of China
  
• 刊物主题：Analytical Chemistry; Biotechnology; Organic Chemistry; Proteomics; Bioinformatics;
• 出版者：Springer US
• ISSN：1879-1123

文摘

The specific locations of the double bonds in linear olefins can facilitate olefin catalytic synthetic reactions to improve the quality of target olefin products. We developed a simple and efficient approach based on single photon ionization time-of-flight mass spectrometry (SPI-TOFMS) combined with online ozonolysis to identify and quantify the linear olefin double bond positional isomers. The online ozonolysis cleaved the olefins at the double bond positions that led to formation of corresponding characteristic aldehydes. The aldehydes were then detected by SPI-TOFMS to achieve unique spectrometric “fingerprints” for each linear olefin to successfully identify the isomeric ones. To accurately quantify the isomeric components in olefin mixtures, an algorithm was proposed to quantify three isomeric olefin mixtures based on characteristic ion intensities and their equivalent ionization coefficients. The relative concentration errors for the olefin components were lower than 2.5% while the total analysis time was less than 2 min. These results demonstrate that the online ozonolysis SPI-TOFMS has the potential for real-time monitoring of catalytic olefin synthetic reactions.