Resistive index of prostatic capsular arteries as a predictor of prostate cancer in patients undergoing initial prostate biopsy

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• 作者：Xuefeng Zhang (1)
  Gang Li (1)
  Linkun Hu (1)
  Xuedong Wei (1)
  Yueqin Zha (2)
  Huming Yin (1)
  Mubin Sun (1)
  Jun He (1)
  Jianquan Hou (1)
  
• 关键词：Resistive index of prostatic capsular artery ; Prostate cancer ; Transrectal color Doppler ultrasonography ; Gleason score
• 刊名：Medical Oncology
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：31
• 期：12
• 全文大小：1,301 KB
• 参考文献：1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71-6. CrossRef
  2. Heidenreich A, Aus G, Bolla M, et al. EAU guidelines on prostate cancer. Eur Urol. 2008;53:68-0. CrossRef
  3. Sadeghi-Nejad H, Simmons M, Dakwar G, et al. Controversies in transrectal ultrasonography and prostate biopsy. Ultrasound Q. 2006;22:169-5. CrossRef
  4. Mitterberger M, Horninger W, Aigner F, et al. Ultrasound of the prostate. Cancer Imaging. 2010;10:40-. CrossRef
  5. Turgut AT, Olcücüoglu E, Kosar P, et al. Power doppler ultrasonography of the feeding arteries of the prostate gland: a novel approach to the diagnosis of prostate cancer? J Ultrasound Med. 2007;26:875-3.
  6. Kojima M, Ochiai A, Naya Y, et al. Doppler resistive index in benign prostatic hyperplasia: correlation with ultrasonic appearance of the prostate and infravesical obstruction. Eur Urol. 2000;37:436-2. CrossRef
  7. Shinbo H, Kurita Y, Takada S, et al. Resistive index as risk factor for acute urinary retention in patients with benign prostatic hyperplasia. Urology. 2010;76:1440-. CrossRef
  8. Jiang H, Liu F, Wang Z, et al. Prediction of prostate cancer from prostate biopsy in Chinese men using a genetic score derived from 24 prostate cancer risk-associated SNPs. Prostate. 2013;73:1651-.
  9. Pallwein L, Mitterberger M, Pelzer A, et al. Ultrasound of prostate cancer: recent advances. Eur Radiol. 2008;18:707-5. CrossRef
  10. Tsuru N, Kurita Y, Suzuki K, et al. Resistance index in benign prostatic hyperplasia using power Doppler imaging and clinical outcomes after transurethral vaporization of the prostate. Int J Urol. 2005;12:264-. CrossRef
  11. Huang T, Qi J, Yu YJ, et al. Predictive value of resistive index, detrusor wall thickness and ultrasound estimated bladder weight regarding the outcome after transurethral prostatectomy for patients with lower urinary tract symptoms suggestive of benign prostatic obstruction. Int J Urol. 2012;19:343-0. CrossRef
  12. Zhang XF, Li G, Wei XD, et al. Resistive index of prostate capsular arteries: a newly identified parameter to diagnose and assess bladder outlet obstruction in patients with benign prostatic hyperplasia. J Urol. 2012;188:881-. CrossRef
  13. Chevli KK, Duff M, Walter P, et al. Urinary PCA3 as a predictor of prostate caner in a cohort of 3073 men undergoing initial prostate biopsy. J Urol. 2014;191:1743-. CrossRef
  14. Tang J, Li S, Li J, et al. Correlation between prostate cancer grade and vascularity on color Doppler imaging: preliminary findings. J Clin Ultrasound. 2003;31:61-. CrossRef
  15. Huang ST, Hsieh ML. Evaluation of resistance index in patients with prostate cancer. Anticancer Res. 2008;28:1985-.
  
• 作者单位：Xuefeng Zhang (1)
  Gang Li (1)
  Linkun Hu (1)
  Xuedong Wei (1)
  Yueqin Zha (2)
  Huming Yin (1)
  Mubin Sun (1)
  Jun He (1)
  Jianquan Hou (1)
  
  1. Department of Urology, The First Affiliated Hospital of Soochow University, 188 Shizi Rd, Suzhou, 215006, People’s Republic of China
  2. Department of Ultrasound, The First Affiliated Hospital of Soochow University, 188 Shizi Rd, Suzhou, 215006, People’s Republic of China
  
• ISSN：1559-131X

文摘

To evaluate the value of resistive index (RI) of prostatic capsular arteries in diagnosis and evaluation of prostate cancer (PCa) in Chinese patients undergoing initial prostate biopsy. A total of 532 consecutive patients undergoing prostate biopsy were enrolled in this study. RI was measured on the largest transverse section of prostate for each individual. The predictive value of RI was evaluated using multivariate logistic regression and receiver operating characteristic (ROC) curve analyses. PCa was identified in 217 (40.79?%) patients. RI was 0.69?±?0.08 and 0.8?±?0.08 for patients without and with PCa (p?PCa (p?PCa in all patients [area under ROC curve (AUC)?=?0.83, 0.78, respectively]. With the cutoff value of 0.73, RI discriminated PCa from non-PCa patients with 81.9?% sensitivity, 75.9?% specificity and 77.63?% diagnostic accuracy. Furthermore, The AUC for RI in the discrimination of PCa from non-PCa patients in a subset with PSA of 4 to 10?ng/ml, high grade from non-high grade PCa patients and advanced from localized PCa patients was 0.70, 0.77 and 0.80, higher than other parameters (p?PCa and predicting the grade and stage of PCa before initial prostate biopsy. The value of RI should be further explored in the future.