Combination of inverted pyramidal nanovoid with silver nanoparticles to obtain further enhancement and its detection for ricin

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• 作者：Meng Wang (1)
  Bin Wang (1)
  Shixuan Wu (1)
  Tingke Guo (1)
  Haoyu Li (1)
  Zhaoqing Guo (1)
  Junhua Wu (2)
  Peiyuan Jia (2)
  Yuxia Wang (2)
  Xiaoxuan Xu (1)
  Yufang Wang (1)
  Cunzhou Zhang (1)
  
  1. The MOE Key Laboratory of Weak Light Nonlinear Photonics ; School of physics and Teda Applied Physics Institute ; Nankai University ; Tianjin ; 300071 ; China
  2. Institute of Pharmacology and Toxicology ; Academy of Military Medical Sciences ; Beijing ; 100850 ; China
  
• 关键词：Surface ; enhanced Raman scattering ; Ricin toxin ; Combined substrate ; Finite element method ; 73.20.Mf ; 74.25.nd ; 81.07. ; b
• 刊名：Nanoscale Research Letters
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：10
• 期：1
• 全文大小：2,519 KB
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• 刊物主题：Nanotechnology; Nanotechnology and Microengineering; Nanoscale Science and Technology; Nanochemistry; Molecular Medicine;
• 出版者：Springer US
• ISSN：1556-276X

文摘

We have obtained the surface-enhanced Raman scattering substrate by depositing silver nanoparticles on the surface of the inverted pyramidal nanovoid in order to improve the enhance effects. Experimental results showed that the combined substrate exhibited greater enhancement than the nanovoid substrate or nanoparticles. In order to test the SERS activity of the combined substrates, Rh6G and ricin toxin were used as Raman probes. Finite element method was employed to simulate electric field and induced charge distribution of the substrates, which have been used to explore the interaction between nanoparticles and nanovoid as well as mechanism of the great enhancement.