The anti-angiogenic role of discoidin domain receptor 2 (DDR2) in laser-induced choroidal neovascularization
详细信息 查看全文
- 作者：Tong Zhu (1)
Jie Zhu (1)
Xin Bu (2)
Hu Zhao (2)
Shuya Zhang (3)
Yuan Chang (1)
Rong Li (1) (4)
Libo Yao (2)
Yusheng Wang (1)
Jin Su (2) - 关键词：DDR2 ; Choroidal neovascularization ; Collagen receptor ; Extracellular matrix
- 刊名：Journal of Molecular Medicine
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：93
- 期：2
- 页码：187-198
- 全文大小：8,200 KB
- 参考文献：1. Calabrese A, Bernard JB, Hoffart L, Faure G, Barouch F, Conrath J, Castet E (2011) Wet versus dry age-related macular degeneration in patients with central field loss: different effects on maximum reading speed. Invest Ophthalmol Vis Sci 52:2417鈥?424 CrossRef
2. Campochiaro PA (2000) Retinal and choroidal neovascularization. J Cell Physiol 184:301鈥?10 CrossRef
3. Torres RJ, Maia M, Muccioli C, Winter G, Souza GK, Pasqualotto LR, Luchini A, Precoma DB (2009) Modifiable risk factors for age-related macular degeneration. Arq Bras Oftalmol 72:406鈥?12 CrossRef
4. Campa C, Costagliola C, Incorvaia C, Sheridan C, Semeraro F, De Nadai K, Sebastiani A, Parmeggiani F (2010) Inflammatory mediators and angiogenic factors in choroidal neovascularization: pathogenetic interactions and therapeutic implications. Mediat Inflamm 2010
5. Shi X, Semkova I, Muther PS, Dell S, Kociok N, Joussen AM (2006) Inhibition of TNF-alpha reduces laser-induced choroidal neovascularization. Exp Eye Res 83:1325鈥?334 CrossRef
6. Krzystolik MG, Afshari MA, Adamis AP, Gaudreault J, Gragoudas ES, Michaud NA, Li W, Connolly E, O'Neill CA, Miller JW (2002) Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment. Arch Ophthalmol 120:338鈥?46 CrossRef
7. Lazic R, Gabric N (2007) Intravitreally administered bevacizumab (Avastin) in minimally classic and occult choroidal neovascularization secondary to age-related macular degeneration. Graefes arch Clin Exp Ophthalmology=Albrecht von Graefes Archiv fur klin Exp Ophthalmol 245:68鈥?3 CrossRef
8. Barber NA, Ganti AK (2011) Pulmonary toxicities from targeted therapies: a review. Target Oncol 6:235鈥?43 CrossRef
9. Buyukoglan H, Gulmez I, Tutar N, Oymak FS, Kanbay A, Demir R (2011) Gluteal abscess: an unusual complication of Bacille Calmette-Guerin. Anna Thorac Med 6:235鈥?36 CrossRef
10. Obayashi Y, Yamadori I, Fujita J, Yoshinouchi T, Ueda N, Takahara J (1997) The role of neutrophils in the pathogenesis of idiopathic pulmonary fibrosis. Chest 112:1338鈥?343 CrossRef
11. Vogel W, Gish GD, Alves F, Pawson T (1997) The discoidin domain receptor tyrosine kinases are activated by collagen. Mol Cell 1:13鈥?3 CrossRef
12. Vogel WF, Abdulhussein R, Ford CE (2006) Sensing extracellular matrix: an update on discoidin domain receptor function. Cell Signal 18:1108鈥?116 CrossRef
13. Badiola I, Olaso E, Crende O, Friedman SL, Vidal-Vanaclocha F (2012) Discoidin domain receptor 2 deficiency predisposes hepatic tissue to colon carcinoma metastasis. Gut 61:1465鈥?472 CrossRef
14. Olaso E, Arteta B, Benedicto A, Crende O, Friedman SL (2011) Loss of discoidin domain receptor 2 promotes hepatic fibrosis after chronic carbon tetrachloride through altered paracrine interactions between hepatic stellate cells and liver-associated macrophages. Am J Pathol 179:2894鈥?904 CrossRef
15. Olaso E, Lin HC, Wang LH, Friedman SL (2011) Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling. Fibrogenesis Tissue Repair 4:5 CrossRef
16. Xu L, Servais J, Polur I, Kim D, Lee PL, Chung K, Li Y (2010) Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice. Arthritis Rheum 62:2736鈥?744 CrossRef
17. Zhang S, Bu X, Zhao H, Yu J, Wang Y, Li D, Zhu C, Zhu T, Ren T, Liu X et al (2014) A host deficiency of discoidin domain receptor 2 (DDR2) inhibits both tumour angiogenesis and metastasis. J Pathol 232:436鈥?48 CrossRef
18. Kano K, Marin de Evsikova C, Young J, Wnek C, Maddatu TP, Nishina PM, Naggert JK (2008) A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse. Mol Endocrinol 22:1866鈥?880 CrossRef
19. Kim LG, Thompson SG, Marteau TM, Scott RA, Multicentre Aneurysm Screening Study G (2004) Screening for abdominal aortic aneurysms: the effects of age and social deprivation on screening uptake, prevalence and attendance at follow-up in the MASS trial. J Med Screen 11:50鈥?3 CrossRef
20. Zhang Y, Su J, Yu J, Bu X, Ren T, Liu X, Yao L (2011) An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation. J Bone Miner Res 26:604鈥?17 CrossRef
21. Yang XM, Wang YS, Zhang J, Li Y, Xu JF, Zhu J, Zhao W, Chu DK, Wiedemann P (2009) Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization. Invest Ophthalmol Vis Sci 50:1873鈥?879 CrossRef
22. Li X, Cai Y, Wang YS, Shi YY, Hou W, Xu CS, Wang HY, Ye Z, Yao LB, Zhang J (2012) Hyperglycaemia exacerbates choroidal neovascularisation in mice via the oxidative stress-induced activation of STAT3 signalling in RPE cells. PLoS One 7:e47600 CrossRef
23. Monteagudo B, Labandeira J, Cabanillas M, Acevedo A, Leon-Muinos E, Toribio J (2012) Prevalence of milia and palatal and gingival cysts in Spanish newborns. Pediatr Dermatol 29:301鈥?05 CrossRef
24. Zhang Y, Tanner KE (2008) Effect of filler surface morphology on the impact behaviour of hydroxyapatite reinforced high density polyethylene composites. J Mater Sci Mater Med 19:761鈥?66 CrossRef
25. Campochiaro PA, Soloway P, Ryan SJ, Miller JW (1999) The pathogenesis of choroidal neovascularization in patients with age-related macular degeneration. Mol Vis 5:34
26. Nowak JZ (2006) Age-related macular degeneration (AMD): pathogenesis and therapy. Pharmacol Rep: PR 58:353鈥?63
27. Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N (1998) Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 273:30336鈥?0343 CrossRef
28. Gille H, Kowalski J, Yu L, Chen H, Pisabarro MT, Davis-Smyth T, Ferrara N (2000) A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3-kinase activation and endothelial cell migration. EMBO J 19:4064鈥?073 CrossRef
29. Maliba R, Lapointe S, Neagoe PE, Brkovic A, Sirois MG (2006) Angiopoietins-1 and 鈭? are both capable of mediating endothelial PAF synthesis: intracellular signalling pathways. Cell Signal 18:1947鈥?957 CrossRef
30. Wu X, Liu N (2010) The role of Ang/Tie signaling in lymphangiogenesis. Lymphology 43:59鈥?2
31. Samalavichius NE (2004) [Preventive Turnbull ileostomy]. Khirurgiia (Mosk):50鈥?2
32. Lee JE, Kang CS, Guan XY, Kim BT, Kim SH, Lee YM, Moon WS, Kim DK (2007) Discoidin domain receptor 2 is involved in the activation of bone marrow-derived dendritic cells caused by type I collagen. Biochem Biophys Res Commun 352:244鈥?50 CrossRef
33. Baxa U, Taylor KL, Steven AC, Wickner RB (2004) Prions of saccharomyces and Podospora. Contrib Microbiol 11:50鈥?1 CrossRef
34. Chen SC, Wang BW, Wang DL, Shyu KG (2008) Hypoxia induces discoidin domain receptor-2 expression via the p38 pathway in vascular smooth muscle cells to increase their migration. Biochem Biophys Res Commun 374:662鈥?67 CrossRef
35. Lee NO, Park JW, Lee JA, Shim JH, Kong SY, Kim KT, Lee YS (2012) Dual action of a selective cyclooxygenase-2 inhibitor on vascular endothelial growth factor expression in human hepatocellular carcinoma cells: novel involvement of discoidin domain receptor 2. J Cancer Res Clin Oncol 138:73鈥?4 CrossRef - 作者单位：Tong Zhu (1)
Jie Zhu (1)
Xin Bu (2)
Hu Zhao (2)
Shuya Zhang (3)
Yuan Chang (1)
Rong Li (1) (4)
Libo Yao (2)
Yusheng Wang (1)
Jin Su (2)
1. Department of Ophthalmology, Xijing Hospital, The Fourth Military Medical University, 169 Changle Western Road, Xi鈥檃n, 710032, China
2. State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, 169 Changle Western Road, Xi鈥檃n, 710032, China
3. Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Department of Biochemistry and Molecular Biology, Ningxia Medical University, Yinchuan, China
4. Affiliated hospital of Xi鈥檃n Medical University, Xi鈥檃n, 710077, China - 刊物类别：Biomedical and Life Sciences
- 刊物主题：Biomedicine
Molecular Medicine
Internal Medicine - 出版者：Springer Berlin / Heidelberg
- ISSN：1432-1440
文摘