Yam Contributes to Improvement of Glucose Metabolism in Rats

详细信息    查看全文

• 作者：Naoto Hashimoto (1)
  Takahiro Noda (1)
  Sun-Ju Kim (1)
  Md Zaidul Islam Sarker (1) (3)
  Hiroaki Yamauchi (1)
  Shigenobu Takigawa (1)
  Chie Matsuura-Endo (1)
  Tatsuro Suzuki (1)
  Kyu-Ho Han (2)
  Michihiro Fukushima (2)
  
• 关键词：Glycemia ; Glycemic index ; Insulinemia ; Leptin ; Rats ; Yams
• 刊名：Plant Foods for Human Nutrition
• 出版年：2009
• 出版时间：September 2009
• 年：2009
• 卷：64
• 期：3
• 页码：193-198
• 全文大小：142KB
• 参考文献：1. Mauvais-Jarvis F, Andreelli F, Hanaire-Broutin H, Charbonnel B, Girard J (2001) Therapeutic perspectives for type 2 diabetes mellitus: molecular and clinical insights. Diabetes Metab 27:415鈥?23
  2. Nelson BA, Robinson KA, Buse MG (2002) Defective Akt activation is associated with glucose鈥?but not glucosamine-induced insulin resistance. Am J Physiol Endocrinol Metab 282:E497鈥?06
  3. Chaikomin R, Rayner CK, Jones KL, Horowitz M (2006) Upper gastrointestinal function and glycemic control in diabetes mellitus. World J Gastroenterol 12:5611鈥?621
  4. Jenkins DJ, Kendall CW, Augustin LS, Franceschi S, Hamidi M, Marchie A, Jenkins AL, Axelsen M (2002) Glycemic index: overview of implications in health and disease. Am J Clin Nutr 76:266S鈥?73S
  5. Wright E Jr, Scism-Bacon JL, Glass LC (2006) Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia. Int J Clin Pract 60:308鈥?14 ss="external" href="http://dx.doi.org/10.1111/j.1368-5031.2006.00825.x">CrossRef
  6. Ceriello A (2005) Postprandial hyperglycemia and diabetes complications: is it time to treat? Diabetes 54:1鈥? ss="external" href="http://dx.doi.org/10.2337/diabetes.54.1.1">CrossRef
  7. Augustin LS, Franceschi S, Jenkins DJ, Kendall CW, La Vecchia C (2002) Glycemic index in chronic disease: a review. Eur J Clin Nutr 56:1049鈥?071 ss="external" href="http://dx.doi.org/10.1038/sj.ejcn.1601454">CrossRef
  8. Wylie-Rosett J, Segal-Isaacson CJ, Segal-Isaacson A (2004) Carbohydrates and increases in obesity: does the type of carbohydrate make a difference? Obes Res 12(Suppl 2):124S鈥?29S ss="external" href="http://dx.doi.org/10.1038/oby.2004.277">CrossRef
  9. Jenkins DJ, Wolever TM, Leeds AR, Gassull MA, Haisman P, Dilawari J, Goff DV, Metz GL, Alberti KG (1978) Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity. Br Med J 1:1392鈥?394 ss="external" href="http://dx.doi.org/10.1136/bmj.1.6124.1392">CrossRef
  10. Williams JA, Lai CS, Corwin H, Ma Y, Maki KC, Garleb KA, Wolf BW (2004) Inclusion of guar gum and alginate into a crispy bar improves postprandial glycemia in humans. J Nutr 134:886鈥?89
  11. Vuksan V, Sievenpiper JL, Xu Z, Wong EY, Jenkins AL, Beljan-Zdravkovic U, Leiter LA, Josse RG, Stavro MP (2001) onjac-Mannan and American ginsing: emerging alternative therapies for type 2 diabetes mellitus. J Am Coll Nutr 20:370S鈥?80S discussion 381聽S-383 S
  12. van de Laar FA, Lucassen PL, Akkermans RP, van de Lisdonk EH, Rutten GE, van Weel C (2005) Alpha-glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis. Diabetes Care 28:154鈥?63 ss="external" href="http://dx.doi.org/10.2337/diacare.28.1.154">CrossRef
  13. Casirola DM, Ferraris RP (2006) Alpha-glucosidase inhibitors prevent diet-induced increases in intestinal sugar transport in diabetic mice. Metabolism 55:832鈥?41 ss="external" href="http://dx.doi.org/10.1016/j.metabol.2006.02.011">CrossRef
  14. Hanamura T, Mayama C, Aoki H, Hirayama Y, Shimizu M (2006) Antihyperglycemic effect of polyphenols from Acerola ( / Malpighia emarginata DC.) fruit. Biosci Biotechnol Biochem 70:1813鈥?820 ss="external" href="http://dx.doi.org/10.1271/bbb.50592">CrossRef
  15. Iwai K, Kim MY, Onodera A, Matsue H (2006) Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of / Viburnum dilatatum Thunb. J Agric Food Chem 54:4588鈥?592 ss="external" href="http://dx.doi.org/10.1021/jf0606353">CrossRef
  16. Guo H, Ling W, Wang Q, Liu C, Hu Y, Xia M, Feng X, Xia X (2007) Effect of anthocyanin-rich extract from black rice ( / Oryza sativa L. indica) on hyperlipidemia and insulin resistance in fructose-fed rats. Plant Foods Hum Nutr 62:1鈥? ss="external" href="http://dx.doi.org/10.1007/s11130-006-0031-7">CrossRef
  17. Hee-Jeong J, Ming-Jung K, Tae-Jin S, Hyuu-A K, Sung-Ja Y, Soo-Kyung L, Hwa-Jae L, Boo-Hyeong B, Jung-In K (2006) The hypoglycemic effect of Saururus chinensis Baill in animal models of diabetes mellitus. Food Sci. Biotechnol. 15:413鈥?17
  18. Hikino H, Konno C, Takahashi M, Murakami M, Kato Y, Karikura M, Hayashi T (1986) Isolation and hypoglycemic activity of dioscorans A, B, C, D, E, and F; glycans of Dioscorea japonica rhizophors. Planta Med 52:168鈥?71 ss="external" href="http://dx.doi.org/10.1055/s-2007-969112">CrossRef
  19. Tsukui M, Nagashima T, Sato H, Kozuma TT, Tanimura W (1999) Characterization of Yam ( / Dioscorea opposita Thunb.) Mucilage and Polysaccharide with Different Varieties. Nippon Shokuhin Kagaku Kogaku Kaishi 46:575鈥?80
  20. Hashimoto N, Hara H (2003) Dietary amino acids promote pancreatic protease synthesis at the translation stage in rats. J Nutr 133:3052鈥?057
  21. Bunn HF, Gabbay KH, Gallop PM (1978) The glycosylation of hemoglobin: relevance to diabetes mellitus. Science 200:21鈥?7 ss="external" href="http://dx.doi.org/10.1126/science.635569">CrossRef
  22. Toyoshima Y, Gavrilova O, Yakar S, Jou W, Pack S, Asghar Z, Wheeler MB, LeRoith D (2005) Leptin improves insulin resistance and hyperglycemia in a mouse model of type 2 diabetes. Endocrinology 146:4024鈥?035 ss="external" href="http://dx.doi.org/10.1210/en.2005-0087">CrossRef
  23. Steinberg GR, Rush JW, Dyck DJ (2003) AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment. Am J Physiol Endocrinol Metab 284:E648鈥?54
  24. Dube JJ, Bhatt BA, Dedousis N, Bonen A, O鈥橠oherty RM (2007) Leptin, skeletal muscle lipids, and lipid-induced insulin resistance. Am J Physiol Regul Integr Comp Physiol 293:R642鈥?50
  25. El-Haschimi K, Pierroz DD, Hileman SM, Bjorbaek C, Flier JS (2000) Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 105:1827鈥?832 ss="external" href="http://dx.doi.org/10.1172/JCI9842">CrossRef
  26. Yamazaki M, Nishimura T (1992) Induction of neutrophil accumulation by vegetable juice. Biosci Biotechnol Biochem 56:150鈥?51 ss="external" href="http://dx.doi.org/10.1271/bbb.56.150">CrossRef
  27. McAnuff MA, Harding WW, Omoruyi FO, Jacobs H, Morrison EY, Asemota HN (2005) Hypoglycemic effects of steroidal sapogenins isolated from Jamaican bitter yam, / Dioscorea polygonoides. Food Chem Toxicol 43:1667鈥?672 ss="external" href="http://dx.doi.org/10.1016/j.fct.2005.05.008">CrossRef
  28. McAnuff-Harding MA, Omoruyi FO, Asemota HN (2006) Intestinal disaccharidases and some renal enzymes in streptozotocin-induced diabetic rats fed sapogenin extract from bitter yam (Dioscorea polygonoides). Life Sci 78:2595鈥?600 ss="external" href="http://dx.doi.org/10.1016/j.lfs.2005.10.046">CrossRef
  29. Hou WC, Hsu FL, Lee MH (2002) Yam (Dioscorea batatas) tuber mucilage exhibited antioxidant activities / in vitro. Planta Med 68:1072鈥?076 ss="external" href="http://dx.doi.org/10.1055/s-2002-36356">CrossRef
  30. Jeon JR, Lee JS, Lee CH, Kim JY, Kim SD, Nam DH (2006) Effect of ethanol extract of dried Chinese yam (Dioscorea batatas) flour containing dioscin on gastrointestinal function in rat model. Arch Pharm Res 29:348鈥?53 ss="external" href="http://dx.doi.org/10.1007/BF02968583">CrossRef
  
• 作者单位：Naoto Hashimoto (1)
  Takahiro Noda (1)
  Sun-Ju Kim (1)
  Md Zaidul Islam Sarker (1) (3)
  Hiroaki Yamauchi (1)
  Shigenobu Takigawa (1)
  Chie Matsuura-Endo (1)
  Tatsuro Suzuki (1)
  Kyu-Ho Han (2)
  Michihiro Fukushima (2)
  
  1. Memuro Upland Farming Research Station, National Agricultural Research Center for Hokkaido Region, Memuro, Hokkaido, 082-0081, Japan
  3. Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, DE, Malaysia
  2. Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080-8555, Japan
  

文摘

To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0聽g of a control and 20% yam-containing diets. At 60聽min after start of the feeding, glucose level in the yam diet group was lower or tended to be lower than that in the control diet. Insulin levels at 30聽min and 60聽min were significantly lower than those in the control group. In a long-term experiment, a normal diet (N) or 25% high fat diets with (Y) or without 15% yam powder (HF) were given to rats for 4聽weeks. At 4聽weeks, in an oral glucose tolerance test, the area under the curve (AUC) of plasma glucose level was higher in the HF group than that in the N group, whereas those in the Y groups did not differ from that in the N group. Glycosylated hemoglobin levels had similar tendency to the AUCs. Plasma leptin levels in the Y groups were significantly higher than that in the N group. In conclusion, yam may contribute to improvement of glucose metabolism. Additionally, we speculated that leptin level is possibly involved in the insulin-response to yam diets.