Expansion of the Milan criteria without any sacrifice: combination of the Hangzhou criteria with the pre-transplant platelet-to-lymphocyte ratio

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• 作者：Weiliang Xia ; Qinghong Ke ; Hua Guo ; Weilin Wang ; Min Zhang ; Yan Shen ; Jian Wu&#8230
• 关键词：Hangzhou criteria ; Liver transplantation ; Hepatocellular carcinoma ; Platelet ; to ; lymphocyte ratio
• 刊名：BMC Cancer
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：969KB
• 刊物主题：Cancer Research; Oncology; Surgical Oncology; Health Promotion and Disease Prevention; Biomedicine, general; Medicine/Public Health, general;
• 出版者：BioMed Central
• ISSN：1471-2407
• 卷排序：17

文摘

BackgroundThe Hangzhou criteria expand the Milan criteria safely and effectively in selecting hepatocellular carcinoma (HCC) candidates for liver transplantation (LT), but some patients exceeding the Milan but fulfilling the Hangzhou criteria still show poor outcomes due to early tumor recurrence. In this study, the platelet-to-lymphocyte ratio (PLR) was employed to differentiate high-risk tumor recurrence recipients, and a new method combining PLR and the Hangzhou criteria was established.