Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer
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- 作者：Chun Wang ; Zhaomei Mu ; Inna Chervoneva…
- 关键词：Circulating tumor cells (CTCs) ; Circulating tumor cell clusters (CTC ; clusters) ; Metastatic breast cancer (MBC) ; Prognosis ; Time ; dependent analysis
- 刊名：Breast Cancer Research and Treatment
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：161
- 期：1
- 页码：83-94
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Oncology;
- 出版者：Springer US
- ISSN：1573-7217
- 卷排序：161
文摘
PurposeCirculating tumor cell (CTC) is a well-established prognosis predictor for metastatic breast cancer (MBC), and CTC-cluster exhibits significantly higher metastasis-promoting capability than individual CTCs. Because measurement of CTCs and CTC-clusters at a single time point may underestimate their prognostic values, we aimed to analyze longitudinally collected CTCs and CTC-clusters in MBC prognostication.