参考文献:1. Tsai M C, Manor O, Wan Y, / et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science, 2010, 329: 689鈥?93 CrossRef 2. Ponting C P, Oliver P L, Reik W. Evolution and functions of long noncoding RNAs. Cell, 2009, 136: 629鈥?41 CrossRef 3. Wilusz J E, Sunwoo H, Spector D L. Long noncoding RNAs: functional surprises from the RNA world. Genes Dev, 2009, 23: 1494鈥?504 CrossRef 4. Huang W T, Guo X Q, Dai J P, / et al. MicroRNA and lncRNA in neurodegenerative diseases. Prog Biochem Biophys, 2010, 37: 826鈥?33 CrossRef 5. Yang C, Wei W. The miRNA expression profile of the uveal melanoma. Sci China Life Sci, 2011, 54: 351鈥?58 CrossRef 6. Feng Y, Yu X. Cardinal roles of miRNA in cardiac development and disease. Sci China Life Sci, 2012, 54: 1113鈥?120 CrossRef 7. Lin B B, Zhang Y, Xu Y, / et al. The main miRNA regulators Drosha and Dicer are associated with ectopic endometrium. Prog Biochem Biophys, 2012, 39: 78鈥?5 CrossRef 8. Liang J W, Wang P, Chen L, / et al. miR-133b may regulate mouse B cell development by targeting the transcription factor foxO1. Prog Biochem Biophys, 2011, 38: 744鈥?50 CrossRef 9. Chen H, Chen Q, Fang M, / et al. microRNA-181b targets MLK2 in HL-60 cells. Sci China Life Sci, 2010, 53: 101鈥?06 CrossRef 10. Luo J, Teng M, Fan J, / et al. Marek鈥檚 disease virus-encoded microRNAs: genomics, expression and function. Sci China Life Sci, 2010, 53: 1174鈥?180 CrossRef 11. Yan L M, Wu J Y, Yu X H, / et al. Role of intronic microRNA in the regulation of endothelial nitric oxide synthase expression and the proliferation of endothelial cells. Prog Biochem Biophys, 2010, 37: 747鈥?53 CrossRef 12. Chen W J, Yin K, Zhao G J, / et al. microRNAs: a new mechanisms for regulation of lipid metabolism. Prog Biochem Biophys, 2011, 38: 781鈥?90 CrossRef 13. Ding Y F, Zhu C, Wang S S, / et al. Regulation of heavy metal stress response by plant microRNAs. Prog Biochem Biophys, 2011, 38: 1106鈥?110 CrossRef 14. Jin Y F, Xu G M, Li Y, / et al. A novel normalization approach for microRNA quantitative PCR. Prog Biochem Biophys, 2011, 38: 473鈥?81 CrossRef 15. Li S, Yu B, Wang Y, / et al. Identification and functional annotation of novel microRNAs in the proximal sciatic nerve after sciatic nerve transection. Sci China Life Sci, 2011, 54: 806鈥?12 CrossRef 16. Wang G, Dong X, Hu J, / et al. Long-term / ex vivo monitoring of / in vivo microRNA activity in liver using a secreted luciferase sensor. Sci China Life Sci, 2011, 54: 418鈥?25 CrossRef 17. Zuo J, Wang Y, Liu H, / et al. MicroRNAs in tomato plants. Sci China Life Sci, 2011, 54: 599鈥?05 CrossRef 18. Feng W, Feng Y. MicroRNAs in neural cell development and brain diseases. Sci China Life Sci, 2012, 54: 1103鈥?112 CrossRef 19. Gong Z J, Huang H B, Xu K, / et al. Advances in microRNAs and TP53 gene regulatory network. Prog Biochem Biophys, 2012, 39:1133鈥?144 20. Li J, Wei H, Li Y, / et al. Identification of a suitable endogenous control gene in porcine blastocysts for use in quantitative PCR analysis of microRNAs. Sci China Life Sci, 2012, 55: 126鈥?31 CrossRef 21. Yu J, Wang F. Recent progress in microRNA study: benefits from technique advance. Sci China Life Sci, 2012, 55: 649鈥?50 CrossRef 22. Zhang Y. Progress, challenges and new concepts in microRNAs. Sci China Life Sci, 2012, 54: 1096 CrossRef 23. Zhang Y, Dong D, Yang B. Atrial remodeling in atrial fibrillation and association between microRNA network and atrial fibrillation. Sci China Life Sci, 2012, 54: 1097鈥?102 CrossRef 24. Ye L, Zhang G Y, Liu T, / et al. Construction of combination gene vector expressing VEGF-siRNA and fusion suicide gene yCDglyTK and its application. Prog Biochem Biophys, 2010, 37: 503鈥?09 CrossRef 25. Zhang Y, Zu X Y, Luo W S, / et al. siRNA induced cyclinB1 knockdown sensitizes HepG2 cells to daunorubicin. Prog Biochem Biophys, 2011, 38: 551鈥?57 CrossRef 26. Chen R S. Delivery: a principal challenge in siRNA application. Prog Biochem Biophys, 2012, 39: 395 27. Dong W J, Zhou Y J, Liang W. Lipid-based siRNA delivery systems. Prog Biochem Biophys, 2012, 39: 396鈥?01 CrossRef 28. Wang H J, Yin J Q. The effects of cell penetrating peptides structure modification on their siRNA delivery function / in vitro and / in vivo. Prog Biochem Biophys, 2012, 39: 402鈥?09 CrossRef 29. Jiang L, Wei C, Li Y. Viral suppression of RNA silencing. Sci China Life Sci, 2012, 55: 109鈥?18 CrossRef 30. Tan Y, Zhang X M. Aptamer mediated delivery of small interfering RNAs. Prog Biochem Biophys, 2012, 39: 410鈥?15 CrossRef 31. Zhu H, Guo H. The role of virus-derived small interfering RNAs in RNA silencing in plants. Sci China Life Sci, 2012, 55: 119鈥?25 CrossRef 32. Zheng J, Zheng B J, Fang F, / et al. Mitochondrial tRNA mutations associated with hearing loss. Prog Biochem Biophys, 2012, 39: 22鈥?0 CrossRef 33. Qi G. The background of the total synthesis of yeast alanine transfer RNA. Sci China Life Sci, 2010, 53: 19鈥?1 CrossRef 34. Chen X, Wang E D. Transfer RNA-derived Small RNAs: degradation fragments or novel regulatory molecules? Prog Biochem Biophys, 2011, 38: 681鈥?87 CrossRef 35. Li X, Wu Z, Fu X, / et al. Long noncoding RNAs: insights from biological features and functions to diseases. Med Res Rev, 2012 36. Yap K L, Li S, Munoz-Cabello A M, / et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell, 2010, 38: 662鈥?74 CrossRef 37. Rinn J L, Kertesz M, Wang J K, / et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell, 2007, 129: 1311鈥?323 CrossRef 38. Liang X, Ma J, Schatten H, / et al. Epigenetic changes associated with oocyte aging. Sci China Life Sci, 2012, 55: 670鈥?76 CrossRef 39. Huang H, Jiao R. Roles of chromatin assembly factor 1 in the epigenetic control of chromatin plasticity. Sci China Life Sci, 2012, 55: 15鈥?9 CrossRef 40. Chao S, Li J, Jin X, / et al. Epigenetic reprogramming of embryos derived from sperm frozen at -20 degrees C. Sci China Life Sci, 2012, 55: 349鈥?57 CrossRef 41. Bi X. Functions of chromatin remodeling factors in heterochromatin formation and maintenance. Sci China Life Sci, 2012, 55: 89鈥?6 CrossRef 42. Ling H Y, Hu B, Feng S D, / et al. The role of epigenetic regulation in diabetes and its complications. Prog Biochem Biophys, 2012, 39: 14鈥?1 CrossRef 43. Imamura T, Yamamoto S, Ohgane J, / et al. Non-coding RNA directed DNA demethylation of Sphk1 CpG island. Biochem Biophys Res Commun, 2004, 322: 593鈥?00 CrossRef 44. Martens J A, Laprade L, Winston F. Intergenic transcription is required to repress the / Saccharomyces cerevisiae SER3 gene. Nature, 2004, 429: 571鈥?74 CrossRef 45. Martianov I, Ramadass A, Serra Barros A, / et al. Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript. Nature, 2007, 445: 666鈥?70 CrossRef 46. Mariner P D, Walters R D, Espinoza C A, / et al. Human Alu RNA is a modular transacting repressor of mRNA transcription during heat shock. Mol Cell, 2008, 29: 499鈥?09 CrossRef 47. Beltran M, Puig I, Pena C, / et al. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. Genes Dev, 2008, 22: 756鈥?69 CrossRef 48. Gibb E A, Brown C J, Lam W L. The functional role of long non-coding RNA in human carcinomas. Mol Cancer, 2011, 10: 38 CrossRef 49. Yang F, Zhang L, Huo X S, / et al. Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology, 2011, 54: 1679鈥?689 CrossRef 50. Khaitan D, Dinger M E, Mazar J, / et al. The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Res, 2011, 71: 3852鈥?862 CrossRef 51. Matouk I J, DeGroot N, Mezan S, / et al. The H19 non-coding RNA is essential for human tumor growth. PLoS One, 2007, 2: e845 CrossRef 52. Barsyte-Lovejoy D, Lau S K, Boutros P C, / et al. The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis. Cancer Res, 2006, 66: 5330鈥?337 CrossRef 53. Berteaux N, Lottin S, Monte D, / et al. H19 mRNA-like noncoding RNA promotes breast cancer cell proliferation through positive control by E2F1. J Biol Chem, 2005, 280: 29625鈥?9636 CrossRef 54. Tsang W P, Ng E K, Ng S S, / et al. Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis, 2010, 31: 350鈥?58 CrossRef 55. Yu W, Gius D, Onyango P, / et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature, 2008, 451: 202鈥?06 CrossRef 56. Pasmant E, Sabbagh A, Vidaud M, / et al. ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS. FASEB J, 2011, 25: 444鈥?48 CrossRef 57. Wilusz J E, Freier S M, Spector D L. 3鈥?end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell, 2008, 135: 919鈥?32 CrossRef 58. Perez D S, Hoage T R, Pritchett J R, / et al. Long, abundantly expressed non-coding transcripts are altered in cancer. Hum Mol Genet, 2008, 17: 642鈥?55 CrossRef 59. Ji P, Diederichs S, Wang W, / et al. MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene, 2003, 22: 8031鈥?041 CrossRef 60. Tano K, Mizuno R, Okada T, / et al. MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes. FEBS Lett, 2010, 584: 4575鈥?580 CrossRef 61. Guo F, Li Y, Liu Y, / et al. Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion. Acta Biochim Biophys Sin, 2010, 42: 224鈥?29 CrossRef 62. Tripathi V, Ellis J D, Shen Z, / et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell, 2010, 39: 925鈥?38 CrossRef 63. Li L, Feng T, Lian Y, / et al. Role of human noncoding RNAs in the control of tumorigenesis. Proc Natl Acad Sci USA, 2009, 106: 12956鈥?2961 CrossRef 64. Gupta R A, Shah N, Wang K C, / et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature, 2010, 464: 1071鈥?076 CrossRef 65. Yang Z, Zhou L, Wu L M, / et al. Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann Surg Oncol, 2011, 18: 1243鈥?250 CrossRef 66. Zhang X, Rice K, Wang Y, / et al. Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions. Endocrinology, 2010, 151: 939鈥?47 CrossRef 67. Zhou Y, Zhang X, Klibanski A. MEG3 noncoding RNA: a tumor suppressor. J Mol Endocrinol, 2012, 48: R45鈥?3 CrossRef 68. Benetatos L, Vartholomatos G, Hatzimichael E. MEG3 imprinted gene contribution in tumorigenesis. Int J Cancer, 2011, 129: 773鈥?79 CrossRef 69. Zhou Y, Zhong Y, Wang Y, / et al. Activation of p53 by MEG3 non-coding RNA. J Biol Chem, 2007, 282: 24731鈥?4742 CrossRef 70. Miao J W, Zhang Y Q, Xu C Y, / et al. Involvement of P16(INK4a) and sonic hedgehog signaling pathways in squamous cell carcinoma of uterine cervix and its precursor lesions. Prog Biochem Biophys, 2012, 39: 671鈥?77 CrossRef 71. Gordon F E, Nutt C L, Cheunsuchon P, / et al. Increased expression of angiogenic genes in the brains of mouse meg3-null embryos. Endocrinology, 2010, 151: 2443鈥?452 CrossRef 72. Morris K V, Santoso S, Turner A M, / et al. Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet, 2008, 4: e1000258 CrossRef 73. Wang X, Arai S, Song X, / et al. Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature, 2008, 454: 126鈥?30 CrossRef 74. Tinzl M, Marberger M, Horvath S, / et al. DD3PCA3 RNA analysis in urine-a new perspective for detecting prostate cancer. Eur Urol, 2004, 46: 182鈥?86 CrossRef
作者单位:ZhaoJian Gong (1) (2) (3) ShanShan Zhang (4) WenLing Zhang (2) HongBin Huang (2) (5) Qiao Li (2) Hao Deng (1) Jian Ma (1) (2) Ming Zhou (1) (2) JuanJuan Xiang (1) (2) MingHua Wu (1) (2) XiaYu Li (1) Wei Xiong (1) (2) XiaoLing Li (1) (2) Yong Li (6) ZhaoYang Zeng (1) (2) GuiYuan Li (1) (2)
1. Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, the Third Xiangya Hospital, Central South University, Changsha, 410013, China 2. Key Laboratory of Carcinogenesis of Ministry of Health, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Cancer Research Institute, Central South University, Changsha, 410078, China 3. Department of Stomatology, the Second Xiangya Hospital, Central South University, Changsha, 410011, China 4. Department of Stomatology, Xiangya Hospital, Central South University, Changsha, 410008, China 5. Key Laboratory of Information System Engineering, National University of Defense Technology, Changsha, 410073, China 6. Department of Biochemistry and Molecular Biology, Center for Genetics and Molecular Medicine, School of Medicine, University of Louisville, Louisville, KY, 40202, USA