Development of a New Certified Reference Material of Kaempferol by Using Differential Scanning Calorimetry, Coulometric Titration Method, and Mass Balance Method

详细信息    查看全文

• 作者：Ningbo Gong ; Guoshun Zhang ; Baoxi Zhang ; Guanhua Du ; Zhaolin Gao…
• 关键词：Kaempferol ; Differential scanning calorimetry ; Coulometric titration ; Mass balance method ; Certified reference material
• 刊名：Food Analytical Methods
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：8
• 期：9
• 页码：2347-2355
• 全文大小：306 KB
• 参考文献：An H, Wang H, Lan Y, Hashi Y, Chen S (2013) Simultaneous qualitative and quantitative analysis of phenolic acids and flavonoids for the quality control of Apocynum venetum L. leaves by HPLC–DAD–ESI–IT–TOF–MS and HPLC–DAD. J Pharm Biomed Anal 85:295-04CrossRef
  Bruni G, Berbenni V, Milanese C et al (2011) Determination of the nateglinide polymorphic purity through DSC. J Pharm Biomed Anal 54:1196-199CrossRef
  Byun MR, Jeong H, Bae SJ, Kim AR, Hwang ES, Hong JH (2012) TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol. Bone 50:364-72CrossRef
  Canini A, Alesiani D, D’Arcangelo G, Tagliatesta P (2007) Gas chromatography–mass spectrometry analysis of phenolic compounds from Carica papaya L. leaf. J Food Compos Anal 20:584-90CrossRef
  Chen X, Yang X, Liu T et al (2012) Kaempferol regulates MAPKs and NF-κB signaling pathways to attenuate LPS-induced acute lung injury in mice. Int Immunopharmacol 14:209-16CrossRef
  Choi EM (2011) Kaempferol protects MC3T3-E1 cells through antioxidant effect and regulation of mitochondrial function. Food Chem Toxicol 49:1800-805CrossRef
  García-Mediavilla V, Crespo I, Collado PS et al (2007) The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang liver cells. Eur J Pharmacol 557:221-29CrossRef
  G?decke T, Napolitano JG, Rodríguez-Brasco MF et al (2013) Validation of a generic quantitative (1)H NMR method for natural products analysis. Phytochem Anal 24:581-97CrossRef
  Goff TL, Wood S (2008) Production of malachite green oxalate and leucomalachite green reference materials certified for purity. Anal Bioanal Chem 391:2035-045CrossRef
  Gong NB, Liu SC, Xu W et al (2013) Purity assessment of luteolin reference material candidates by coulometric titration method. Anal Methods 5:784-88CrossRef
  Grundmann O, Nakajima J, Kamata K, Seo S, Butterweck V (2009) Kaempferol from the leaves of Apocynum venetum possesses anxiolytic activities in the elevated plus maze test in mice. Phytomedicine 16:295-02CrossRef
  Han L, Liu XH, Yang NY, Li JS, Cai BC, Cheng S (2012) Simultaneous chromatographic fingerprinting and quantitative analysis of flavonoids in Pollen Typhae by high-performance capillary electrophoresis. Acta Pharm Sin B 2:602-09CrossRef
  ISO Guide 34 (2009) General requirements for the competence of reference material producers. International Organization for Standardization, Geneva
  ISO Guide 35 (2006) Reference materials—general and statistical principles for certification. International Organization for Standardization, Geneva
  Johnson D, Rettinger M, Tarbox T, Marek B, Pogue S, Dilek I, Sreenivasan U (2013) Development challenges in the preparation of solution-based phytochemical and vitamin certified reference materials. Anal Bioanal Chem 405:4345-352CrossRef
  Koch M, Bremser W, Koeppen R, Siegel D, Toepfer A, Nehls I (2009) Development of two certified reference materials for acrylamide determination in foods. J Agric Food Chem 57:8202-207CrossRef
  Medeiros KC, Faustino L, Borduchi E et al (2009) Preventive and curative glycoside kaempferol treatments attenuate the TH2-driven allergic airway disease. Int Immunopharmacol 9:1540-548CrossRef
  Mylonis I, Lakka A, Tsakalof A, Simos G (2010) The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions. Biochem Biophys Res Commun 398:74-8CrossRef
  Trivedi R, Kumar S, Kumar A, Siddiqui JA, Chattopadhyay N et al (2008) Kaempferol has osteogenic effect in ovariectomized adult Sprague–Dawley rats. Mol Cell Endocrinol 289:85-3CrossRef
  Wood LJ, Sharpless KE, Pichon M, Porter BJ, Yen JH (2011) Characterization of three berry standard reference materials for nutrients. J Agric Food Chem 59:7246-252CrossRef
  Xiao J, Sun GB, Sun B et al (2012) Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. Toxicology 292:53-2CrossRef
  Zu Y, Li C, Fu Y, Zhao C (2006) Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. J Pharm Biomed Anal 41:714-19CrossRef
  
• 作者单位：Ningbo Gong (1)
  Guoshun Zhang (1)
  Baoxi Zhang (1)
  Guanhua Du (2)
  Zhaolin Gao (3)
  Yang Lu (1) (3)
  
  1. Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
  2. Beijing City Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
  3. Key Laboratory of Polymorph Pharmaceutical of Shandong Province, Tengzhou, 277500, China
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Food Science
  Chemistry
  Microbiology
  Analytical Chemistry
  
• 出版者：Springer New York
• ISSN：1936-976X

文摘

Dietary flavonols have been found to possess preventive and therapeutic potential against several kinds of cancers. According to epidemiologic investigation data, kaempferol is a major component of flavonols present in various natural sources such as herbs, vegetables, and fruits. The purity of kaempferol in candidate certified reference material (CRM) was based on the agreement of results obtained by three different methods, including differential scanning calorimetry (DSC), coulometric titration (CT), and mass balance method. The certified value of kaempferol CRM is 99.5 % with an expanded uncertainty of 0.2 % (k--). The new CRM of kaempferol can be used as a valuable tool to validate measurement methods, to evaluate analytical results, and to control the quality of kaempferol-related traditional herbs, foods, dietary supplements, and pharmaceutical formulations.